Primary Malignant Melanoma of the Bladder Treated by Robotic Partial Cystectomy and Immunotherapy

Fahad M. Chaus, Miguel Craig, Erika Bracamonte, Srinath Sundararajan, Benjamin R. Lee

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Primary malignant melanoma (PMM) of the urinary tract is a rare entity, with only 28 cases reported in the literature. We present an interesting case of a 27-year-old Caucasian woman, with family history of melanoma, who initially presented with gross hematuria, and was subsequently found to have PMM of the bladder. Case Presentation: Initially diagnosis was made through transurethral resection of the bladder tumor with clinical suspicion of residual disease in the patient. Subsequently, she underwent robotic partial cystectomy with pelvic lymph node dissection followed by 1 year of pembrolizumab, a PD-1 checkpoint inhibitor. Subsequent imaging demonstrated no evidence of metastatic disease or local recurrence. Conclusion: This case report presents a unique management of a rare pathological diagnosis with the use of robotic partial cystectomy, and a PD-1 checkpoint inhibitor therapy that ultimately has led to a 2-year recurrence-free survival period for this young patient.

Original languageEnglish (US)
Pages (from-to)151-153
Number of pages3
JournalJournal of Endourology Case Reports
Volume5
Issue number4
DOIs
StatePublished - Dec 2019

Keywords

  • bladder tumor
  • immunotherapy
  • melanoma
  • pembrolizumab
  • primary malignant melanoma
  • robotic partial cystectomy

ASJC Scopus subject areas

  • Urology

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