Large optic fabrication is a delicate and time consuming process. Obtaining a large prime optic is often in the critical path of a project and poses a serious risk to both the schedule and budget. The Optical Engineering and Fabrication Facility (OEFF) at the College of Optical Sciences, the University of Arizona, has developed a new way of optimizing its large optic fabrication process for maximum efficiency in convergence. The new process optimization takes the amount of stock material removal, tool characteristics, metrology uncertainty, optic prescription, optic material properties, and resource availability as input parameters and provides an optimized process along with an achievable convergence. This paper presents technical details of the new process optimization and demonstrates performance on 6.5m mirror fabrication at the University of Arizona. Two case studies for an 8.4m GMT off-axis primary mirror segment and a 3.1m TMT convex secondary mirror fabrication are also presented.