Prognostic and therapeutic importance of the aortic diastolic pressure in resuscitation from cardiac arrest

A. B. Sanders, G. A. Ewy, T. V. Taft

Research output: Contribution to journalArticle

173 Scopus citations

Abstract

A study was done to determine if 12 dogs could be resuscitated from 30 min of ventricular fibrillation if aortic diastolic blood pressure was maintained above 30 mm Hg by administration of epinephrine and, in 6 cases, saline solution during cardiopulmonary resuscitation (CPR). Of the 12 dogs seven were resuscitated successfully. The survivors received 3.4 ± 1.7 mg of epinephrine, whereas the nonsurvivors received 11.1 ± 2.1 mg of epinephrine. The aortic diastolic blood pressure was significantly higher (p < .05) in the survivors at 12, 18, 24, and 30 min of ventricular fibrillation. In all nonsurvivors, it was impossible to maintain diastolic pressure above 30 mm Hg even with large doses of epinephrine and saline. Maintenance of an adequate diastolic blood pressure during CPR appears important for survival.

Original languageEnglish (US)
Pages (from-to)871-873
Number of pages3
JournalCritical care medicine
Volume12
Issue number10
DOIs
StatePublished - Jan 1 1984

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

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