Prolonged operating room time in emergency general surgery is associated with venous thromboembolic complications

Joseph V. Sakran, Hiba Ezzeddine, Elliot R. Haut, Nicole Lunardi, Ambar Mehta, Rachel L. Choron, Jennifer Reid, Muhammad Zeeshan, Mohammad Hamidi, Bellal A Joseph

Research output: Contribution to journalArticle


Background: We evaluated the association between operating room time and developing a deep vein thrombosis (DVT)or pulmonary embolus (PE)after emergency general surgery (EGS). Methods: We reviewed six common EGS procedures in the 2013–2015 NSQIP dataset. After tabulating their incidence of postoperative VTE events, we calculated predictors of developing a VTE using adjusted multivariate logistic regressions. Results: Of 108,954 EGS patients, 1,366 patients (1.3%)developed a VTE postoperatively. The median time to diagnosis was 9 days [5–16]for DVTs and 8 days [5–16]for PEs. Operating room time of 100 min or more was associated with increased risk of developing a DVT (OR 1.30 [1.12–2.21])and PE (OR:1.25 [1.11–2.43])with a 7% and 5% respective increase for every 10 min increase after the 100 min. Other independent predictors of VTE complications were older age, and history of cancer, and emergent colectomies on procedure-level analysis. Conclusion: Prolonged operating room time is independently associated with increased risk of developing VTE complications after an EGS procedure. Most of the VTE complications were delayed in presentation.

Original languageEnglish (US)
JournalAmerican journal of surgery
Publication statusPublished - Jan 1 2019
Externally publishedYes



  • Deep venous thrombosis
  • Emergency general surgery
  • Prolonged operative time
  • Pulmonary embolism
  • Venous thromboembolism

ASJC Scopus subject areas

  • Surgery

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