Promoting adherence to treatment for latent TB infection through mobile phone text messaging: Study protocol for a pilot randomized controlled trial

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Background: An estimated two billion people, over one third of the world's population, have latent infection with Mycobacterium tuberculosis (LTBI). Patient adherence to LTBI treatment is currently poor given that individuals show no symptoms of illness and may not feel that they are at risk of developing active tuberculosis (TB). Short text messages can serve as a simple reminder to take medications and address barriers to adherence such as forgetfulness and lack of social support. Methods/design: We aim to determine the feasibility and acceptability of text reminders for improving adherence in latent TB patients using a randomized controlled single-blinded trial, measuring adherence through an increase in treatment completion rates. Forty adult LTBI participants will be randomized to either text messages plus phone call reminders or phone call reminders only (usual care). Recruitment, retention, and study acceptability will be assessed as primary outcomes. Discussion: This pilot study will examine the feasibility of using text messaging for increasing adherence to treatment for latent tuberculosis infection. The study will allow for evaluation of process measures and challenges and development of a model for scaling up an effectiveness trial for increasing treatment adherence.

Original languageEnglish (US)
Article number15
JournalPilot and Feasibility Studies
Volume3
Issue number1
DOIs
StatePublished - Dec 20 2017

Keywords

  • Latent tuberculosis infection
  • Text messages
  • Treatment adherence

ASJC Scopus subject areas

  • Medicine (miscellaneous)

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