Prophylactic Human Papillomavirus Vaccination: A Breakthrough in Primary Cervical Cancer Prevention

Francisco A.R. Garcia, Debbie Saslow

Research output: Contribution to journalReview article

10 Scopus citations

Abstract

Nearly all cervical cancers require human papillomavirus infection (HPV) for subsequent carcinogenesis. The identification of this obligate viral etiology, in addition to a vast knowledge about the HPV viral life cycle and resultant host response, has led to a vaccine approach to cervical cancer prevention. The use of prophylactic cancer vaccine as primary prevention holds the most promise for long-term cancer prevention but raises some important and as yet unanswered questions that are addressed in this article.

Original languageEnglish (US)
Pages (from-to)761-781
Number of pages21
JournalObstetrics and Gynecology Clinics of North America
Volume34
Issue number4
DOIs
StatePublished - Dec 1 2007

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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