Prostate-specific antigen obtained under optimal conditions determines extracapsular adenocarcinoma of the prostate

J. T. Ehreth, J. I. Miller, R. B. McBeath, K. K. Hansen, Frederick R Ahmann, B. L. Dalkin, M. Schiff

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Objective: To assess the relationship of prostate-specific antigen (PSA) obtained under optimal conditions with the presence or absence of organ-confined prostate cancer following radical prostatectomy. Patients and methods: The medical records of 300 consecutive patients who underwent radical retropubic prostatectomy were retrospectively reviewed. Ninety-three patients were excluded who had a pre-operative PSA level potentially altered by various factors (prostate infection, manipulation or instrumentation). Results: A pre-operative PSA value <4 ng/mL accurately predicted pathologically confined disease in 42 of 51 patients (82%) which contrasted with extracapsular disease in 74 of 84 patients (88%) who had a PSA value > 10 ng/mL. One of the 53 patients with a PSA > 15 ng/mL had organ-confined disease at surgery. Conclusion: These data demonstrate that optimal serum PSA values correlate well with pathological stage.

Original languageEnglish (US)
Pages (from-to)21-25
Number of pages5
JournalBritish Journal of Urology
Volume75
Issue number1
StatePublished - 1995

Fingerprint

Prostate-Specific Antigen
Prostate
Adenocarcinoma
Prostatectomy
Medical Records
Prostatic Neoplasms
Infection
Serum

Keywords

  • organ-confined
  • prostate cancer
  • prostate-specific antigen

ASJC Scopus subject areas

  • Urology

Cite this

Ehreth, J. T., Miller, J. I., McBeath, R. B., Hansen, K. K., Ahmann, F. R., Dalkin, B. L., & Schiff, M. (1995). Prostate-specific antigen obtained under optimal conditions determines extracapsular adenocarcinoma of the prostate. British Journal of Urology, 75(1), 21-25.

Prostate-specific antigen obtained under optimal conditions determines extracapsular adenocarcinoma of the prostate. / Ehreth, J. T.; Miller, J. I.; McBeath, R. B.; Hansen, K. K.; Ahmann, Frederick R; Dalkin, B. L.; Schiff, M.

In: British Journal of Urology, Vol. 75, No. 1, 1995, p. 21-25.

Research output: Contribution to journalArticle

Ehreth, JT, Miller, JI, McBeath, RB, Hansen, KK, Ahmann, FR, Dalkin, BL & Schiff, M 1995, 'Prostate-specific antigen obtained under optimal conditions determines extracapsular adenocarcinoma of the prostate', British Journal of Urology, vol. 75, no. 1, pp. 21-25.
Ehreth, J. T. ; Miller, J. I. ; McBeath, R. B. ; Hansen, K. K. ; Ahmann, Frederick R ; Dalkin, B. L. ; Schiff, M. / Prostate-specific antigen obtained under optimal conditions determines extracapsular adenocarcinoma of the prostate. In: British Journal of Urology. 1995 ; Vol. 75, No. 1. pp. 21-25.
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