PROTECT: A coordinated stroke treatment program to prevent recurrent thromboembolic events

B. Ovbiagele, J. L. Saver, A. Fredieu, S. Suzuki, N. McNair, A. Dandekar, T. Razinia, C. S. Kidwell

Research output: Contribution to journalArticle

82 Scopus citations

Abstract

Objective: To assess the impact of the Preventing Recurrence of Thromboembolic Events through Coordinated Treatment (PROTECT) Program on achievement of its eight secondary prevention goals at the time of discharge. Methods: Achievement rates for the eight program goals at time of discharge were compared in all patients discharged from a university hospital-based stroke service with a diagnosis of ischemic stroke or TIA during a 1-year period after implementation of the PROTECT Program vs rates obtained from a comparable group of patients admitted to the same service during the preceding year. Results: Demographic and medical features were comparable in the baseline and intervention cohorts for all patients with cerebral ischemia presumed due to large-vessel atherosclerosis or small-vessel disease (baseline year n = 117, intervention n = 130). Implementation rates in patients without specific contraindications increased for all four medication goals: 97 to 100% for antithrombotic agents, 68 to 97% for statins, 42 to 90% for angiotensin- converting enzyme inhibitors/angiotensin receptor blockers, and 14 to 70% for diuretics. Although data were not collected on baseline lifestyle instruction rates, instruction in the program's four lifestyle interventions was achieved by discharge in 100% of the intervention cohort. Conclusion: Implementation of this single-center, systems-based, inhospital program to initiate secondary stroke prevention therapies was associated with a substantial increase in treatment utilization at the time of hospital discharge.

Original languageEnglish (US)
Pages (from-to)1217-1222
Number of pages6
JournalNeurology
Volume63
Issue number7
DOIs
StatePublished - Oct 12 2004
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Neurology

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    Ovbiagele, B., Saver, J. L., Fredieu, A., Suzuki, S., McNair, N., Dandekar, A., Razinia, T., & Kidwell, C. S. (2004). PROTECT: A coordinated stroke treatment program to prevent recurrent thromboembolic events. Neurology, 63(7), 1217-1222. https://doi.org/10.1212/01.WNL.0000140493.83607.F1