Protein transsport through a separation membrane in a microfluidic device

Timothy S. Frost, Victor Estrada, Linan Jiang, Yitshak Zohar

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The effects of several design parameters on the transient and steady-state transport of molecules between an upper and lower microchannels separated by a porous membrane were studied experimentally and numerically. While the flow rate and membrane porosity were found to be the dominant effects, changing the flow direction, molecular size, or channel height had little effect. The simulations reveal that the molecular diffusion is confined to a short distance from the membrane.

Original languageEnglish (US)
Title of host publication22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
PublisherChemical and Biological Microsystems Society
Pages1976-1978
Number of pages3
ISBN (Electronic)9781510897571
StatePublished - Jan 1 2018
Event22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 - Kaohsiung, Taiwan, Province of China
Duration: Nov 11 2018Nov 15 2018

Publication series

Name22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
Volume4

Conference

Conference22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
CountryTaiwan, Province of China
CityKaohsiung
Period11/11/1811/15/18

Keywords

  • Microfluidics
  • Molecular convection-diffusion
  • Porous membrane
  • Protein transport

ASJC Scopus subject areas

  • Chemistry(all)
  • Bioengineering
  • Chemical Engineering (miscellaneous)
  • Control and Systems Engineering

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