Pseudopsammomatous meningioma with elevated serum carcinoembryonic antigen: A true secretory meningioma. Case report

D. N. Louis, A. J. Hamilton, R. A. Sobel, R. G. Ojemann

Research output: Contribution to journalArticle

37 Scopus citations

Abstract

A sphenoid-wing meningioma in a 60-year-old woman was accompanied by elevated serum carcinoembryonic antigen (CEA) levels, which returned to normal after removal of the tumor. Light microscopic examination revealed a secretory meningioma containing numerous pseudopsammoma bodies and a prominent vascular pattern. Immunohistochemical analysis showed the tumor cells and pseudosammoma bodies to be CEA-positive. This case illustrates the possibility that secretory meningioma may be associated with clinically detectable secretion of CEA. The report also documents the rare occurrence of elevated serum CEA in a primary benign intracranial tumor.

Original languageEnglish (US)
Pages (from-to)129-132
Number of pages4
JournalJournal of neurosurgery
Volume74
Issue number1
DOIs
StatePublished - Jan 1 1991
Externally publishedYes

Keywords

  • carcinoembryonic antigen
  • central nervous system tumor
  • meningioma
  • pseudopsammoma body

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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