Pulmonary adenocarcinomas associated with rheumatoid nodules: A case report and review of the literature

Amy C. Baruch, Karen Steinbronn, Richard E Sobonya

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Necrobiotic lung nodules and primary lung carcinoma both occur with some frequency in patients with rheumatoid arthritis; however, few reports exist of a primary lung carcinoma occurring within a rheumatoid nodule. We report a case of a 62-year-old woman with multiple pulmonary nodules discovered incidentally by computed tomography. Although 2 of the lesions were composed solely of necrotizing granulomas, 2 additional lesions contained malignant glands at the periphery of necrobiotic nodules. Immunohistochemical staining supported the diagnosis of both tumors as primary lung carcinomas. Our literature search revealed only 2 other reported cases of adenocarcinoma occurring in association with a rheumatoid nodule; these cases, as well as the association between rheumatoid disease and malignancy, are briefly reviewed.

Original languageEnglish (US)
Pages (from-to)104-106
Number of pages3
JournalArchives of Pathology and Laboratory Medicine
Volume129
Issue number1
StatePublished - Jan 2005

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Rheumatoid Nodule
Lung
Carcinoma
Multiple Pulmonary Nodules
Granuloma
Rheumatoid Arthritis
Neoplasms
Adenocarcinoma
Tomography
Staining and Labeling
Adenocarcinoma of lung

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

Cite this

Pulmonary adenocarcinomas associated with rheumatoid nodules : A case report and review of the literature. / Baruch, Amy C.; Steinbronn, Karen; Sobonya, Richard E.

In: Archives of Pathology and Laboratory Medicine, Vol. 129, No. 1, 01.2005, p. 104-106.

Research output: Contribution to journalArticle

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