Abstract
Necrobiotic lung nodules and primary lung carcinoma both occur with some frequency in patients with rheumatoid arthritis; however, few reports exist of a primary lung carcinoma occurring within a rheumatoid nodule. We report a case of a 62-year-old woman with multiple pulmonary nodules discovered incidentally by computed tomography. Although 2 of the lesions were composed solely of necrotizing granulomas, 2 additional lesions contained malignant glands at the periphery of necrobiotic nodules. Immunohistochemical staining supported the diagnosis of both tumors as primary lung carcinomas. Our literature search revealed only 2 other reported cases of adenocarcinoma occurring in association with a rheumatoid nodule; these cases, as well as the association between rheumatoid disease and malignancy, are briefly reviewed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 104-106 |
| Number of pages | 3 |
| Journal | Archives of Pathology and Laboratory Medicine |
| Volume | 129 |
| Issue number | 1 |
| State | Published - Jan 2005 |
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ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Medical Laboratory Technology
Cite this
Pulmonary adenocarcinomas associated with rheumatoid nodules : A case report and review of the literature. / Baruch, Amy C.; Steinbronn, Karen; Sobonya, Richard E.
In: Archives of Pathology and Laboratory Medicine, Vol. 129, No. 1, 01.2005, p. 104-106.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Pulmonary adenocarcinomas associated with rheumatoid nodules
T2 - A case report and review of the literature
AU - Baruch, Amy C.
AU - Steinbronn, Karen
AU - Sobonya, Richard E
PY - 2005/1
Y1 - 2005/1
N2 - Necrobiotic lung nodules and primary lung carcinoma both occur with some frequency in patients with rheumatoid arthritis; however, few reports exist of a primary lung carcinoma occurring within a rheumatoid nodule. We report a case of a 62-year-old woman with multiple pulmonary nodules discovered incidentally by computed tomography. Although 2 of the lesions were composed solely of necrotizing granulomas, 2 additional lesions contained malignant glands at the periphery of necrobiotic nodules. Immunohistochemical staining supported the diagnosis of both tumors as primary lung carcinomas. Our literature search revealed only 2 other reported cases of adenocarcinoma occurring in association with a rheumatoid nodule; these cases, as well as the association between rheumatoid disease and malignancy, are briefly reviewed.
AB - Necrobiotic lung nodules and primary lung carcinoma both occur with some frequency in patients with rheumatoid arthritis; however, few reports exist of a primary lung carcinoma occurring within a rheumatoid nodule. We report a case of a 62-year-old woman with multiple pulmonary nodules discovered incidentally by computed tomography. Although 2 of the lesions were composed solely of necrotizing granulomas, 2 additional lesions contained malignant glands at the periphery of necrobiotic nodules. Immunohistochemical staining supported the diagnosis of both tumors as primary lung carcinomas. Our literature search revealed only 2 other reported cases of adenocarcinoma occurring in association with a rheumatoid nodule; these cases, as well as the association between rheumatoid disease and malignancy, are briefly reviewed.
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UR - http://www.scopus.com/inward/citedby.url?scp=11844252529&partnerID=8YFLogxK
M3 - Article
C2 - 15628888
AN - SCOPUS:11844252529
VL - 129
SP - 104
EP - 106
JO - Archives of Pathology and Laboratory Medicine
JF - Archives of Pathology and Laboratory Medicine
SN - 0003-9985
IS - 1
ER -