Pursuing dynamic reorganization in auditory cortex using chronic, multichannel unit recordings in awake, behaving cats

Russell S Witte, K. J. Otto, J. C. Williams, D. R. Kipke

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

We implanted microelectrode arrays bilaterally into auditory cortex of trained cats in order to assess dynamic cortical reorganization. Cats were trained to listen to a series of tone-pip pairs and respond to the pair that had different frequencies. Over several months of training, a gradual decrease ( - 4.2 x 10-4 Weber Fractions/training day) in the frequency discrimination threshold occurred (p < 0.00001). Neural recordings from a trained cat not performing the task were obtained for 5 days. Temporal and frequency response properties remained stable over this time. These techniques are useful for a variety of studies on learning-induced cortical plasticity.

Original languageEnglish (US)
Pages (from-to)593-600
Number of pages8
JournalNeurocomputing
Volume26-27
DOIs
StatePublished - Jun 1999
Externally publishedYes

Fingerprint

Auditory Cortex
Microelectrodes
Frequency response
Plasticity
Cats
Learning

Keywords

  • Auditory cortex
  • Behavior
  • Multichannel electrodes
  • Plasticity

ASJC Scopus subject areas

  • Artificial Intelligence
  • Cellular and Molecular Neuroscience

Cite this

Pursuing dynamic reorganization in auditory cortex using chronic, multichannel unit recordings in awake, behaving cats. / Witte, Russell S; Otto, K. J.; Williams, J. C.; Kipke, D. R.

In: Neurocomputing, Vol. 26-27, 06.1999, p. 593-600.

Research output: Contribution to journalArticle

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