Pyloric stenosis and direct hyperbilirubinemia with alpha-1-antitrypsin deficiency

Fayez K Ghishan, D. R. LaBrecque, F. A. Mitros, M. K. Younoszai

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Abstract

The occurrence of unconjugated hyperbilirubinemia in infants with pyloric stenosis is common. We report an infant who presented with projectile vomiting secondary to pyloric stenosis. In addition, he had conjugated hyperbilirubinemia which proved to be due to alpha-1-antitrypsin deficiency of PiZZ phenotype. This is the first case report of such an association. Infants with pyloric stenosis and conjugated hyperbilirubinemia should be investigated for underlying infectious, metabolic causes or anatomical defects of the biliary tree.

Original languageEnglish (US)
Pages (from-to)293-295
Number of pages3
JournalClinical Pediatrics
Volume19
Issue number4
Publication statusPublished - 1980
Externally publishedYes

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ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Ghishan, F. K., LaBrecque, D. R., Mitros, F. A., & Younoszai, M. K. (1980). Pyloric stenosis and direct hyperbilirubinemia with alpha-1-antitrypsin deficiency. Clinical Pediatrics, 19(4), 293-295.