Quantitative analysis of the EEG in the intracarotid amobarbital procedure. I. Amplitude analysis

Geoffrey L Ahern, David M Labiner, Ronald Hutzler, Cheryl Osburn, Dinesh Talwar, Anne M. Herring, Julie N. Tackenberg, Martin E Weinand, Kalarickal J. Oommen

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Thirty-seven subjects underwent bilateral internal carotid artery injections of amobarbital prior to surgery for intractable epilepsy. The electroencephalogram (EEG) of these patients was continuously monitored during these 74 procedures and was later subjected to quantitative analysis. Topographic mapping of these data suggested that the areas of inactivation were largely restricted to the anterior 2/3 of the hemisphere injected, corresponding to the vascular distributions of the anterior and middle cerebral arteries. Graphical representation of the data demonstrated that delta and theta band activity peaked in the first 2 min post injection and decreased gradually thereafter, becoming stable at around 12 min post injection. Examination of the alpha, beta1, and beta2 bands suggested that activity increased and decreased more gradually than that for delta and theta, with perhaps a longer latency. Although EEG changes were most prominent in the anterior 2/3 of the inactivated hemisphere, similar (though smaller) changes were also observed in both ipsilateral and contralateral zones thought to be outside of the vascular distribution of the internal carotid artery.

Original languageEnglish (US)
Pages (from-to)21-32
Number of pages12
JournalElectroencephalography and Clinical Neurophysiology
Volume91
Issue number1
DOIs
StatePublished - 1994

Fingerprint

Amobarbital
Electroencephalography
Internal Carotid Artery
Injections
Blood Vessels
Anterior Cerebral Artery
Middle Cerebral Artery

Keywords

  • Amobarbital
  • EEG
  • Epilepsy
  • Intracarotid sodium amobarbital (ISA)
  • Quantitative EEG
  • Wada test

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Quantitative analysis of the EEG in the intracarotid amobarbital procedure. I. Amplitude analysis. / Ahern, Geoffrey L; Labiner, David M; Hutzler, Ronald; Osburn, Cheryl; Talwar, Dinesh; Herring, Anne M.; Tackenberg, Julie N.; Weinand, Martin E; Oommen, Kalarickal J.

In: Electroencephalography and Clinical Neurophysiology, Vol. 91, No. 1, 1994, p. 21-32.

Research output: Contribution to journalArticle

Ahern, Geoffrey L ; Labiner, David M ; Hutzler, Ronald ; Osburn, Cheryl ; Talwar, Dinesh ; Herring, Anne M. ; Tackenberg, Julie N. ; Weinand, Martin E ; Oommen, Kalarickal J. / Quantitative analysis of the EEG in the intracarotid amobarbital procedure. I. Amplitude analysis. In: Electroencephalography and Clinical Neurophysiology. 1994 ; Vol. 91, No. 1. pp. 21-32.
@article{db77e33dd509493b944a36a360dd0651,
title = "Quantitative analysis of the EEG in the intracarotid amobarbital procedure. I. Amplitude analysis",
abstract = "Thirty-seven subjects underwent bilateral internal carotid artery injections of amobarbital prior to surgery for intractable epilepsy. The electroencephalogram (EEG) of these patients was continuously monitored during these 74 procedures and was later subjected to quantitative analysis. Topographic mapping of these data suggested that the areas of inactivation were largely restricted to the anterior 2/3 of the hemisphere injected, corresponding to the vascular distributions of the anterior and middle cerebral arteries. Graphical representation of the data demonstrated that delta and theta band activity peaked in the first 2 min post injection and decreased gradually thereafter, becoming stable at around 12 min post injection. Examination of the alpha, beta1, and beta2 bands suggested that activity increased and decreased more gradually than that for delta and theta, with perhaps a longer latency. Although EEG changes were most prominent in the anterior 2/3 of the inactivated hemisphere, similar (though smaller) changes were also observed in both ipsilateral and contralateral zones thought to be outside of the vascular distribution of the internal carotid artery.",
keywords = "Amobarbital, EEG, Epilepsy, Intracarotid sodium amobarbital (ISA), Quantitative EEG, Wada test",
author = "Ahern, {Geoffrey L} and Labiner, {David M} and Ronald Hutzler and Cheryl Osburn and Dinesh Talwar and Herring, {Anne M.} and Tackenberg, {Julie N.} and Weinand, {Martin E} and Oommen, {Kalarickal J.}",
year = "1994",
doi = "10.1016/0013-4694(94)90015-9",
language = "English (US)",
volume = "91",
pages = "21--32",
journal = "Electroencephalography and Clinical Neurophysiology",
issn = "0013-4694",
publisher = "Elsevier BV",
number = "1",

}

TY - JOUR

T1 - Quantitative analysis of the EEG in the intracarotid amobarbital procedure. I. Amplitude analysis

AU - Ahern, Geoffrey L

AU - Labiner, David M

AU - Hutzler, Ronald

AU - Osburn, Cheryl

AU - Talwar, Dinesh

AU - Herring, Anne M.

AU - Tackenberg, Julie N.

AU - Weinand, Martin E

AU - Oommen, Kalarickal J.

PY - 1994

Y1 - 1994

N2 - Thirty-seven subjects underwent bilateral internal carotid artery injections of amobarbital prior to surgery for intractable epilepsy. The electroencephalogram (EEG) of these patients was continuously monitored during these 74 procedures and was later subjected to quantitative analysis. Topographic mapping of these data suggested that the areas of inactivation were largely restricted to the anterior 2/3 of the hemisphere injected, corresponding to the vascular distributions of the anterior and middle cerebral arteries. Graphical representation of the data demonstrated that delta and theta band activity peaked in the first 2 min post injection and decreased gradually thereafter, becoming stable at around 12 min post injection. Examination of the alpha, beta1, and beta2 bands suggested that activity increased and decreased more gradually than that for delta and theta, with perhaps a longer latency. Although EEG changes were most prominent in the anterior 2/3 of the inactivated hemisphere, similar (though smaller) changes were also observed in both ipsilateral and contralateral zones thought to be outside of the vascular distribution of the internal carotid artery.

AB - Thirty-seven subjects underwent bilateral internal carotid artery injections of amobarbital prior to surgery for intractable epilepsy. The electroencephalogram (EEG) of these patients was continuously monitored during these 74 procedures and was later subjected to quantitative analysis. Topographic mapping of these data suggested that the areas of inactivation were largely restricted to the anterior 2/3 of the hemisphere injected, corresponding to the vascular distributions of the anterior and middle cerebral arteries. Graphical representation of the data demonstrated that delta and theta band activity peaked in the first 2 min post injection and decreased gradually thereafter, becoming stable at around 12 min post injection. Examination of the alpha, beta1, and beta2 bands suggested that activity increased and decreased more gradually than that for delta and theta, with perhaps a longer latency. Although EEG changes were most prominent in the anterior 2/3 of the inactivated hemisphere, similar (though smaller) changes were also observed in both ipsilateral and contralateral zones thought to be outside of the vascular distribution of the internal carotid artery.

KW - Amobarbital

KW - EEG

KW - Epilepsy

KW - Intracarotid sodium amobarbital (ISA)

KW - Quantitative EEG

KW - Wada test

UR - http://www.scopus.com/inward/record.url?scp=0028360868&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028360868&partnerID=8YFLogxK

U2 - 10.1016/0013-4694(94)90015-9

DO - 10.1016/0013-4694(94)90015-9

M3 - Article

C2 - 7517841

AN - SCOPUS:0028360868

VL - 91

SP - 21

EP - 32

JO - Electroencephalography and Clinical Neurophysiology

JF - Electroencephalography and Clinical Neurophysiology

SN - 0013-4694

IS - 1

ER -