Quantitative Evaluation of the Optic Nerve Head in Patients with Unilateral Visual Field Loss from Primary Open-angle Glaucoma

Joseph Caprioli, Joseph M. Miller, Marvin Sears

Research output: Contribution to journalArticlepeer-review

79 Scopus citations

Abstract

Measurable structural alterations of the optic nerve head may precede visual field abnormalities in early open-angle glaucoma. The authors studied the optic nerve heads of 10 patients with unilateral visual field loss from primary open-angle glaucoma, and 12 age- and sex-matched normal subjects. Topographic optic nerve head parameters were measured with a system of computerized image analysis (Rodenstock Analyzer, G. Rodenstock Instrumente GMBH, Munich, W. Germany). In patients with asymmetric primary open-angle glaucoma, eyes with normal visual fields had a slightly larger mean (± standard error of the mean) disc rim area (0.90 ± 0.04 mm2) than eyes with glaucomatous visual field defects (0.78 ± 0.05 mm2). However, both sets of eyes in the asymmetric primary open-angle glaucoma patients had smaller mean disc rim areas (P < 0.0007) than did the control group (1.27 ± 0.09 mm2). These findings support the hypothesis that loss of the optic disc rim can be detected before perimetric abnormalities develop in primary open-angle glaucoma.

Original languageEnglish (US)
Pages (from-to)1484-1487
Number of pages4
JournalOphthalmology
Volume94
Issue number11
DOIs
StatePublished - 1987
Externally publishedYes

Keywords

  • glaucoma
  • image analysis
  • optic disc rim area
  • optic nerve
  • perimetry
  • visual field

ASJC Scopus subject areas

  • Ophthalmology

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