Quasi-cyclic codes exhibiting the gene regulatory network of the cell cycle

Vida Ravanmehr, Bane Vasić

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We present an artificial Boolean network exhibiting the behaviour similar to that of the cell cycle: three phases and checkpoints between them. The phases follow the increase of the cell mass, while checkpoints ensure that internal errors are corrected before moving to the next phase. The network can tolerate up to one gene mutation and one transient error in gene expressions. It has only 6 genes and is the smallest and simplest network with such behavior. It is based on a special type of error correction codes, resulting in an elegant and symmetric network topology and highly symmetric attractor basin.

Original languageEnglish (US)
Title of host publication2012 IEEE Symposium on Computational Intelligence and Computational Biology, CIBCB 2012
Pages412-417
Number of pages6
DOIs
StatePublished - Jul 25 2012
Event2012 IEEE Symposium on Computational Intelligence and Computational Biology, CIBCB 2012 - San Diego, CA, United States
Duration: May 9 2012May 12 2012

Publication series

Name2012 IEEE Symposium on Computational Intelligence and Computational Biology, CIBCB 2012

Other

Other2012 IEEE Symposium on Computational Intelligence and Computational Biology, CIBCB 2012
CountryUnited States
CitySan Diego, CA
Period5/9/125/12/12

Keywords

  • Boolean networks
  • cell cycle
  • error correction
  • gene regulatory networks
  • quasi-cyclic codes

ASJC Scopus subject areas

  • Electrical and Electronic Engineering

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    Ravanmehr, V., & Vasić, B. (2012). Quasi-cyclic codes exhibiting the gene regulatory network of the cell cycle. In 2012 IEEE Symposium on Computational Intelligence and Computational Biology, CIBCB 2012 (pp. 412-417). [6217259] (2012 IEEE Symposium on Computational Intelligence and Computational Biology, CIBCB 2012). https://doi.org/10.1109/CIBCB.2012.6217259