Racial Disparities in the Cardiac Computed Tomography Assessment of Coronary Artery Disease

Does Gender Matter

Ayman El-Menyar, Ahmed Abuzaid, Ayman Elbadawi, Matthew McIntyre, Rifat - Latifi

Research output: Contribution to journalReview article

Abstract

Coronary heart disease (CHD) represents a significant healthcare burden in terms of hospital resources, morbidity, and mortality. Primary prevention and early detection of risk factors for the development of CHD are pivotal to successful intervention programs and prognostication. Yet, there remains a paucity of evidence regarding differences in the assessment of these risk factors and the tools of assessment among different ethnicities. We conducted a narrative review to assess the utility of cardiac computed tomography, particularly coronary artery calcification (CAC), in different ethnicities. We also looked to see whether age, sex, comorbidities, and genetic background have peculiar influences on CAC. In this review, we highlight some of the pivotal studies regarding the question of CAC in relation to the development of CHD among different ethnicities. We identify several key trends in the literature showing that although African Americans have high rates of CHD, their risk of CAC may be relatively lower compared with other ethnicities. Similarly, South Asian patients may be at a high risk for adverse cardiac events due to elevated CAC. We also note that several studies are limited by small sample size and were based on 1 large cohort study. Future studies should include a large international prospective cohort to truly evaluate the effects of ethnicity on CAC and CHD risk. To appropriately apply CAC in the clinical practice, the variations in its scoring based on a subject's age, sex, comorbidity, and ethnicity should be addressed and interpreted beforehand.

Original languageEnglish (US)
Pages (from-to)14-22
Number of pages9
JournalCardiology in review
Volume27
Issue number1
DOIs
StatePublished - Jan 1 2019
Externally publishedYes

Fingerprint

Coronary Artery Disease
Coronary Vessels
Tomography
Coronary Disease
Comorbidity
Primary Prevention
African Americans
Sample Size
Cohort Studies
Morbidity
Delivery of Health Care
Mortality

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Racial Disparities in the Cardiac Computed Tomography Assessment of Coronary Artery Disease : Does Gender Matter. / El-Menyar, Ayman; Abuzaid, Ahmed; Elbadawi, Ayman; McIntyre, Matthew; Latifi, Rifat -.

In: Cardiology in review, Vol. 27, No. 1, 01.01.2019, p. 14-22.

Research output: Contribution to journalReview article

El-Menyar, Ayman ; Abuzaid, Ahmed ; Elbadawi, Ayman ; McIntyre, Matthew ; Latifi, Rifat -. / Racial Disparities in the Cardiac Computed Tomography Assessment of Coronary Artery Disease : Does Gender Matter. In: Cardiology in review. 2019 ; Vol. 27, No. 1. pp. 14-22.
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