Radial fast spin-echo method for T2-weighted imaging and T2 mapping of the liver

Maria I Altbach, Eric K. Outwater, Theodore "Ted" Trouard, Elizabeth A Krupinski, Rebecca J. Theilmann, Alison T Stopeck, Mitsuko Kono, Arthur F Gmitro

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

Purpose: To evaluate a multishot radial fast-spin echo (RAD-FSE) method developed to improve the quality of abdominal T2-weighted imaging as well as the characterization of focal liver lesions. Materials and Methods: The RAD-FSE sequence used in this work consisted of a preparatory period followed by a short echo train (ETL = 16). A novel radial k-space trajectory was used to minimize streaking artifacts due to T2 variations and motion. Small diffusion gradients (b = 1.2 mm/s2) were used to improve flow suppression. The quality of images obtained with RAD-FSE was compared to multishot 2DFT fast spin-echo (2DFT-FSE) and half-Fourier acquisition single-shot turbo-spin-echo (HASTE) images using data from 16 patients. A postprocessing algorithm was used to generate multiple high-resolution images (at different effective TE values) as well as a T2 map from a single RAD-FSE data set. The T2 maps were used to differentiate malignant from benign lesions for a set of 33 lesions ranging from 0.8-194 cm3. Results: RAD-FSE produces high-resolution images of the liver in a breath-hold without the motion artifacts of 2DFT-FSE methods, and without the blurriness and loss of small lesion detectability of HASTE. The inclusion of diffusion weighting in RAD-FSE decreases the signal from blood in hepatic vessels, which improves lesion visualization. The T2 values obtained by postprocessing a single RAD-FSE data set can differentiate malignant from benign lesions. The mean T2 values obtained for malignancies, hemangiomas, and cysts are 108 ± 30 msec, 240 ± 14 msec, and 572 ± 334 msec, respectively. Conclusion: These results indicate that RAD-FSE produces abdominal images of higher quality than 2DFT-FSE and HASTE. In addition, lesions can be characterized using T2 maps generated from a single RAD-FSE data set.

Original languageEnglish (US)
Pages (from-to)179-189
Number of pages11
JournalJournal of Magnetic Resonance Imaging
Volume16
Issue number2
DOIs
StatePublished - 2002

Fingerprint

Artifacts
Liver
Hemangioma
Cysts
Datasets
Neoplasms

Keywords

  • Diffusion weighting
  • Fast spin-echo
  • Flow suppression
  • Projection reconstruction MRI
  • Radial MRI
  • T2 measurements

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Radial fast spin-echo method for T2-weighted imaging and T2 mapping of the liver. / Altbach, Maria I; Outwater, Eric K.; Trouard, Theodore "Ted"; Krupinski, Elizabeth A; Theilmann, Rebecca J.; Stopeck, Alison T; Kono, Mitsuko; Gmitro, Arthur F.

In: Journal of Magnetic Resonance Imaging, Vol. 16, No. 2, 2002, p. 179-189.

Research output: Contribution to journalArticle

@article{74dc042fe01d482a81a5ff0145c052e6,
title = "Radial fast spin-echo method for T2-weighted imaging and T2 mapping of the liver",
abstract = "Purpose: To evaluate a multishot radial fast-spin echo (RAD-FSE) method developed to improve the quality of abdominal T2-weighted imaging as well as the characterization of focal liver lesions. Materials and Methods: The RAD-FSE sequence used in this work consisted of a preparatory period followed by a short echo train (ETL = 16). A novel radial k-space trajectory was used to minimize streaking artifacts due to T2 variations and motion. Small diffusion gradients (b = 1.2 mm/s2) were used to improve flow suppression. The quality of images obtained with RAD-FSE was compared to multishot 2DFT fast spin-echo (2DFT-FSE) and half-Fourier acquisition single-shot turbo-spin-echo (HASTE) images using data from 16 patients. A postprocessing algorithm was used to generate multiple high-resolution images (at different effective TE values) as well as a T2 map from a single RAD-FSE data set. The T2 maps were used to differentiate malignant from benign lesions for a set of 33 lesions ranging from 0.8-194 cm3. Results: RAD-FSE produces high-resolution images of the liver in a breath-hold without the motion artifacts of 2DFT-FSE methods, and without the blurriness and loss of small lesion detectability of HASTE. The inclusion of diffusion weighting in RAD-FSE decreases the signal from blood in hepatic vessels, which improves lesion visualization. The T2 values obtained by postprocessing a single RAD-FSE data set can differentiate malignant from benign lesions. The mean T2 values obtained for malignancies, hemangiomas, and cysts are 108 ± 30 msec, 240 ± 14 msec, and 572 ± 334 msec, respectively. Conclusion: These results indicate that RAD-FSE produces abdominal images of higher quality than 2DFT-FSE and HASTE. In addition, lesions can be characterized using T2 maps generated from a single RAD-FSE data set.",
keywords = "Diffusion weighting, Fast spin-echo, Flow suppression, Projection reconstruction MRI, Radial MRI, T2 measurements",
author = "Altbach, {Maria I} and Outwater, {Eric K.} and Trouard, {Theodore {"}Ted{"}} and Krupinski, {Elizabeth A} and Theilmann, {Rebecca J.} and Stopeck, {Alison T} and Mitsuko Kono and Gmitro, {Arthur F}",
year = "2002",
doi = "10.1002/jmri.10142",
language = "English (US)",
volume = "16",
pages = "179--189",
journal = "Journal of Magnetic Resonance Imaging",
issn = "1053-1807",
publisher = "John Wiley and Sons Inc.",
number = "2",

}

TY - JOUR

T1 - Radial fast spin-echo method for T2-weighted imaging and T2 mapping of the liver

AU - Altbach, Maria I

AU - Outwater, Eric K.

AU - Trouard, Theodore "Ted"

AU - Krupinski, Elizabeth A

AU - Theilmann, Rebecca J.

AU - Stopeck, Alison T

AU - Kono, Mitsuko

AU - Gmitro, Arthur F

PY - 2002

Y1 - 2002

N2 - Purpose: To evaluate a multishot radial fast-spin echo (RAD-FSE) method developed to improve the quality of abdominal T2-weighted imaging as well as the characterization of focal liver lesions. Materials and Methods: The RAD-FSE sequence used in this work consisted of a preparatory period followed by a short echo train (ETL = 16). A novel radial k-space trajectory was used to minimize streaking artifacts due to T2 variations and motion. Small diffusion gradients (b = 1.2 mm/s2) were used to improve flow suppression. The quality of images obtained with RAD-FSE was compared to multishot 2DFT fast spin-echo (2DFT-FSE) and half-Fourier acquisition single-shot turbo-spin-echo (HASTE) images using data from 16 patients. A postprocessing algorithm was used to generate multiple high-resolution images (at different effective TE values) as well as a T2 map from a single RAD-FSE data set. The T2 maps were used to differentiate malignant from benign lesions for a set of 33 lesions ranging from 0.8-194 cm3. Results: RAD-FSE produces high-resolution images of the liver in a breath-hold without the motion artifacts of 2DFT-FSE methods, and without the blurriness and loss of small lesion detectability of HASTE. The inclusion of diffusion weighting in RAD-FSE decreases the signal from blood in hepatic vessels, which improves lesion visualization. The T2 values obtained by postprocessing a single RAD-FSE data set can differentiate malignant from benign lesions. The mean T2 values obtained for malignancies, hemangiomas, and cysts are 108 ± 30 msec, 240 ± 14 msec, and 572 ± 334 msec, respectively. Conclusion: These results indicate that RAD-FSE produces abdominal images of higher quality than 2DFT-FSE and HASTE. In addition, lesions can be characterized using T2 maps generated from a single RAD-FSE data set.

AB - Purpose: To evaluate a multishot radial fast-spin echo (RAD-FSE) method developed to improve the quality of abdominal T2-weighted imaging as well as the characterization of focal liver lesions. Materials and Methods: The RAD-FSE sequence used in this work consisted of a preparatory period followed by a short echo train (ETL = 16). A novel radial k-space trajectory was used to minimize streaking artifacts due to T2 variations and motion. Small diffusion gradients (b = 1.2 mm/s2) were used to improve flow suppression. The quality of images obtained with RAD-FSE was compared to multishot 2DFT fast spin-echo (2DFT-FSE) and half-Fourier acquisition single-shot turbo-spin-echo (HASTE) images using data from 16 patients. A postprocessing algorithm was used to generate multiple high-resolution images (at different effective TE values) as well as a T2 map from a single RAD-FSE data set. The T2 maps were used to differentiate malignant from benign lesions for a set of 33 lesions ranging from 0.8-194 cm3. Results: RAD-FSE produces high-resolution images of the liver in a breath-hold without the motion artifacts of 2DFT-FSE methods, and without the blurriness and loss of small lesion detectability of HASTE. The inclusion of diffusion weighting in RAD-FSE decreases the signal from blood in hepatic vessels, which improves lesion visualization. The T2 values obtained by postprocessing a single RAD-FSE data set can differentiate malignant from benign lesions. The mean T2 values obtained for malignancies, hemangiomas, and cysts are 108 ± 30 msec, 240 ± 14 msec, and 572 ± 334 msec, respectively. Conclusion: These results indicate that RAD-FSE produces abdominal images of higher quality than 2DFT-FSE and HASTE. In addition, lesions can be characterized using T2 maps generated from a single RAD-FSE data set.

KW - Diffusion weighting

KW - Fast spin-echo

KW - Flow suppression

KW - Projection reconstruction MRI

KW - Radial MRI

KW - T2 measurements

UR - http://www.scopus.com/inward/record.url?scp=0036021698&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036021698&partnerID=8YFLogxK

U2 - 10.1002/jmri.10142

DO - 10.1002/jmri.10142

M3 - Article

C2 - 12203766

AN - SCOPUS:0036021698

VL - 16

SP - 179

EP - 189

JO - Journal of Magnetic Resonance Imaging

JF - Journal of Magnetic Resonance Imaging

SN - 1053-1807

IS - 2

ER -