Rapid assessment of left ventricular segmental wall motion, ejection fraction, and volumes with single breath-hold, multi-slice TrueFISP MR imaging

David S. Fieno, Louise E J Thomson, Piotr J. Slomka, Aiden Abidov, Hidetaka Nishina, Daisy Chien, Sean W. Hayes, Rola Saouaf, Guido Germano, John D. Friedman, Daniel S. Berman

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Background and Objective: To reduce imaging time and complexity, we sought to determine whether single breath-hold, multi-slice TrueFISP (SB-MST) magnetic resonance imaging (MRI) method is comparable to standard multi-breath-hold, multi-slice TrueFISP (MB-MST) for assessment of left ventricular (LV) wall motion abnormality (WMA), volumes, and ejection fraction (EF). Methods and Results: We studied 62 patients having cardiac MRI at 1.5-Tesla. After acquiring standard MB-MST (one slice per breath-hold), SB-MST was performed, acquiring 3 short- and 2 long-axis views over only 20 heartbeats. Using both techniques, wall motion was scored using a 6-point, 17-segment LV model for all scans (62 patients x 2 techniques/patient = 124 scans) on two separate occasions. Separately, EF and ventricular volumes were evaluated using both MB-MST and SB-MST. For all analyses, MB-MST was considered the standard against which SB-MST was compared. Twenty-six of 62 patients exhibited at least one segmental WMA by MB-MST. Exact agreement for wall motion was found in 965/1054 segments (92%, kappa = 0.74, p < 0.001), and agreement was within 1 score point in 1010/1054 segments (96%). Considering a score >1 abnormal, exact agreement for presence of WMA was found in 131/193 segments (68%) abnormal by MB-MST and for absence of WMA in 838/861 segments (97%) normal by MB-MST. Agreement within 1 score point occurred in 167/193 abnormal (87%) and in 843/861 normal segments (98%). There were no significant differences in agreement between first and second read of the data. Variability of SB-MST on read one versus read two was small (5%, 996/1054 segments read identically, p = ns) and statistically identical to variability of MB-MST on read one versus read two (4%, 1007/1054 segments read identically, p = ns). For end-diastolic volumes, end-systolic volumes, and EF using SB-MST compared to MB-MST, mean differences were 9 ± 15 ml, 6 ± 12 ml, and 2 ± 5%, and correlations were r = 0.97, 0.98 and 0.95, respectively. Conclusion: SB-MST accurately assesses wall motion, volumes and EF. This approach may serve as a screening exam for assessment of WMA and, under select circumstances, may substitute for standard multi-breath-hold method in situations requiring rapid accurate assessments of LV function.

Original languageEnglish (US)
Pages (from-to)435-444
Number of pages10
JournalJournal of Cardiovascular Magnetic Resonance
Volume8
Issue number3
DOIs
StatePublished - 2006
Externally publishedYes

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Magnetic Resonance Imaging
Left Ventricular Function
Stroke Volume

Keywords

  • Cardiac Magnetic Resonance
  • Ejection Fraction
  • Left Ventricular Wall Motion
  • Rapid Imaging
  • Ventricular Volumes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Family Practice

Cite this

Rapid assessment of left ventricular segmental wall motion, ejection fraction, and volumes with single breath-hold, multi-slice TrueFISP MR imaging. / Fieno, David S.; Thomson, Louise E J; Slomka, Piotr J.; Abidov, Aiden; Nishina, Hidetaka; Chien, Daisy; Hayes, Sean W.; Saouaf, Rola; Germano, Guido; Friedman, John D.; Berman, Daniel S.

In: Journal of Cardiovascular Magnetic Resonance, Vol. 8, No. 3, 2006, p. 435-444.

Research output: Contribution to journalArticle

Fieno, David S. ; Thomson, Louise E J ; Slomka, Piotr J. ; Abidov, Aiden ; Nishina, Hidetaka ; Chien, Daisy ; Hayes, Sean W. ; Saouaf, Rola ; Germano, Guido ; Friedman, John D. ; Berman, Daniel S. / Rapid assessment of left ventricular segmental wall motion, ejection fraction, and volumes with single breath-hold, multi-slice TrueFISP MR imaging. In: Journal of Cardiovascular Magnetic Resonance. 2006 ; Vol. 8, No. 3. pp. 435-444.
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abstract = "Background and Objective: To reduce imaging time and complexity, we sought to determine whether single breath-hold, multi-slice TrueFISP (SB-MST) magnetic resonance imaging (MRI) method is comparable to standard multi-breath-hold, multi-slice TrueFISP (MB-MST) for assessment of left ventricular (LV) wall motion abnormality (WMA), volumes, and ejection fraction (EF). Methods and Results: We studied 62 patients having cardiac MRI at 1.5-Tesla. After acquiring standard MB-MST (one slice per breath-hold), SB-MST was performed, acquiring 3 short- and 2 long-axis views over only 20 heartbeats. Using both techniques, wall motion was scored using a 6-point, 17-segment LV model for all scans (62 patients x 2 techniques/patient = 124 scans) on two separate occasions. Separately, EF and ventricular volumes were evaluated using both MB-MST and SB-MST. For all analyses, MB-MST was considered the standard against which SB-MST was compared. Twenty-six of 62 patients exhibited at least one segmental WMA by MB-MST. Exact agreement for wall motion was found in 965/1054 segments (92{\%}, kappa = 0.74, p < 0.001), and agreement was within 1 score point in 1010/1054 segments (96{\%}). Considering a score >1 abnormal, exact agreement for presence of WMA was found in 131/193 segments (68{\%}) abnormal by MB-MST and for absence of WMA in 838/861 segments (97{\%}) normal by MB-MST. Agreement within 1 score point occurred in 167/193 abnormal (87{\%}) and in 843/861 normal segments (98{\%}). There were no significant differences in agreement between first and second read of the data. Variability of SB-MST on read one versus read two was small (5{\%}, 996/1054 segments read identically, p = ns) and statistically identical to variability of MB-MST on read one versus read two (4{\%}, 1007/1054 segments read identically, p = ns). For end-diastolic volumes, end-systolic volumes, and EF using SB-MST compared to MB-MST, mean differences were 9 ± 15 ml, 6 ± 12 ml, and 2 ± 5{\%}, and correlations were r = 0.97, 0.98 and 0.95, respectively. Conclusion: SB-MST accurately assesses wall motion, volumes and EF. This approach may serve as a screening exam for assessment of WMA and, under select circumstances, may substitute for standard multi-breath-hold method in situations requiring rapid accurate assessments of LV function.",
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TY - JOUR

T1 - Rapid assessment of left ventricular segmental wall motion, ejection fraction, and volumes with single breath-hold, multi-slice TrueFISP MR imaging

AU - Fieno, David S.

AU - Thomson, Louise E J

AU - Slomka, Piotr J.

AU - Abidov, Aiden

AU - Nishina, Hidetaka

AU - Chien, Daisy

AU - Hayes, Sean W.

AU - Saouaf, Rola

AU - Germano, Guido

AU - Friedman, John D.

AU - Berman, Daniel S.

PY - 2006

Y1 - 2006

N2 - Background and Objective: To reduce imaging time and complexity, we sought to determine whether single breath-hold, multi-slice TrueFISP (SB-MST) magnetic resonance imaging (MRI) method is comparable to standard multi-breath-hold, multi-slice TrueFISP (MB-MST) for assessment of left ventricular (LV) wall motion abnormality (WMA), volumes, and ejection fraction (EF). Methods and Results: We studied 62 patients having cardiac MRI at 1.5-Tesla. After acquiring standard MB-MST (one slice per breath-hold), SB-MST was performed, acquiring 3 short- and 2 long-axis views over only 20 heartbeats. Using both techniques, wall motion was scored using a 6-point, 17-segment LV model for all scans (62 patients x 2 techniques/patient = 124 scans) on two separate occasions. Separately, EF and ventricular volumes were evaluated using both MB-MST and SB-MST. For all analyses, MB-MST was considered the standard against which SB-MST was compared. Twenty-six of 62 patients exhibited at least one segmental WMA by MB-MST. Exact agreement for wall motion was found in 965/1054 segments (92%, kappa = 0.74, p < 0.001), and agreement was within 1 score point in 1010/1054 segments (96%). Considering a score >1 abnormal, exact agreement for presence of WMA was found in 131/193 segments (68%) abnormal by MB-MST and for absence of WMA in 838/861 segments (97%) normal by MB-MST. Agreement within 1 score point occurred in 167/193 abnormal (87%) and in 843/861 normal segments (98%). There were no significant differences in agreement between first and second read of the data. Variability of SB-MST on read one versus read two was small (5%, 996/1054 segments read identically, p = ns) and statistically identical to variability of MB-MST on read one versus read two (4%, 1007/1054 segments read identically, p = ns). For end-diastolic volumes, end-systolic volumes, and EF using SB-MST compared to MB-MST, mean differences were 9 ± 15 ml, 6 ± 12 ml, and 2 ± 5%, and correlations were r = 0.97, 0.98 and 0.95, respectively. Conclusion: SB-MST accurately assesses wall motion, volumes and EF. This approach may serve as a screening exam for assessment of WMA and, under select circumstances, may substitute for standard multi-breath-hold method in situations requiring rapid accurate assessments of LV function.

AB - Background and Objective: To reduce imaging time and complexity, we sought to determine whether single breath-hold, multi-slice TrueFISP (SB-MST) magnetic resonance imaging (MRI) method is comparable to standard multi-breath-hold, multi-slice TrueFISP (MB-MST) for assessment of left ventricular (LV) wall motion abnormality (WMA), volumes, and ejection fraction (EF). Methods and Results: We studied 62 patients having cardiac MRI at 1.5-Tesla. After acquiring standard MB-MST (one slice per breath-hold), SB-MST was performed, acquiring 3 short- and 2 long-axis views over only 20 heartbeats. Using both techniques, wall motion was scored using a 6-point, 17-segment LV model for all scans (62 patients x 2 techniques/patient = 124 scans) on two separate occasions. Separately, EF and ventricular volumes were evaluated using both MB-MST and SB-MST. For all analyses, MB-MST was considered the standard against which SB-MST was compared. Twenty-six of 62 patients exhibited at least one segmental WMA by MB-MST. Exact agreement for wall motion was found in 965/1054 segments (92%, kappa = 0.74, p < 0.001), and agreement was within 1 score point in 1010/1054 segments (96%). Considering a score >1 abnormal, exact agreement for presence of WMA was found in 131/193 segments (68%) abnormal by MB-MST and for absence of WMA in 838/861 segments (97%) normal by MB-MST. Agreement within 1 score point occurred in 167/193 abnormal (87%) and in 843/861 normal segments (98%). There were no significant differences in agreement between first and second read of the data. Variability of SB-MST on read one versus read two was small (5%, 996/1054 segments read identically, p = ns) and statistically identical to variability of MB-MST on read one versus read two (4%, 1007/1054 segments read identically, p = ns). For end-diastolic volumes, end-systolic volumes, and EF using SB-MST compared to MB-MST, mean differences were 9 ± 15 ml, 6 ± 12 ml, and 2 ± 5%, and correlations were r = 0.97, 0.98 and 0.95, respectively. Conclusion: SB-MST accurately assesses wall motion, volumes and EF. This approach may serve as a screening exam for assessment of WMA and, under select circumstances, may substitute for standard multi-breath-hold method in situations requiring rapid accurate assessments of LV function.

KW - Cardiac Magnetic Resonance

KW - Ejection Fraction

KW - Left Ventricular Wall Motion

KW - Rapid Imaging

KW - Ventricular Volumes

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