Ratiometric and intensity-based zinc sensors built on rhodol and rhodamine platforms

Elisa Tomat, Stephen J. Lippard

Research output: Contribution to journalArticle

74 Citations (Scopus)

Abstract

A xanthene-forming condensation reaction yields rhodol and rhodamine dyes carrying a zinc-binding ligand that includes the aniline-type nitrogen donor of the fluorophores. Upon zinc coordination in neutral aqueous solution, rhodol RF3 behaves as a ratiometric sensor, and rhodamine RA1 acts as a turn-off intensitybased indicator. Both fluorescent compounds bind the divalent zinc cation with micromolar affinity.

Original languageEnglish (US)
Pages (from-to)9113-9115
Number of pages3
JournalInorganic Chemistry
Volume49
Issue number20
DOIs
StatePublished - Oct 18 2010
Externally publishedYes

Fingerprint

Rhodamines
rhodamine
Zinc
Xanthenes
platforms
zinc
Condensation reactions
Fluorophores
sensors
Sensors
Cations
Coloring Agents
Nitrogen
aniline
affinity
condensation
dyes
aqueous solutions
nitrogen
cations

ASJC Scopus subject areas

  • Inorganic Chemistry
  • Physical and Theoretical Chemistry

Cite this

Ratiometric and intensity-based zinc sensors built on rhodol and rhodamine platforms. / Tomat, Elisa; Lippard, Stephen J.

In: Inorganic Chemistry, Vol. 49, No. 20, 18.10.2010, p. 9113-9115.

Research output: Contribution to journalArticle

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