Ratiometric and intensity-based zinc sensors built on rhodol and rhodamine platforms

Elisa Tomat, Stephen J. Lippard

Research output: Contribution to journalArticle

78 Scopus citations

Abstract

A xanthene-forming condensation reaction yields rhodol and rhodamine dyes carrying a zinc-binding ligand that includes the aniline-type nitrogen donor of the fluorophores. Upon zinc coordination in neutral aqueous solution, rhodol RF3 behaves as a ratiometric sensor, and rhodamine RA1 acts as a turn-off intensitybased indicator. Both fluorescent compounds bind the divalent zinc cation with micromolar affinity.

Original languageEnglish (US)
Pages (from-to)9113-9115
Number of pages3
JournalInorganic Chemistry
Volume49
Issue number20
DOIs
StatePublished - Oct 18 2010

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Inorganic Chemistry

Fingerprint Dive into the research topics of 'Ratiometric and intensity-based zinc sensors built on rhodol and rhodamine platforms'. Together they form a unique fingerprint.

  • Cite this