Rational Design of a Highly Efficient Irreversible DNA Interstrand Cross-Linking Agent Based on the Pyrrolobenzodiazepine Ring System

D. Subhas Bose, Andrew S. Thompson, Jingshan Ching, John A. Hartley, Mark D. Berardini, Terence C. Jenkins, Stephen Neidle, Laurence H. Hurley, David E. Thurston

Research output: Contribution to journalArticle

144 Scopus citations
Original languageEnglish (US)
Pages (from-to)4939-4941
Number of pages3
JournalJournal of the American Chemical Society
Volume114
Issue number12
DOIs
StatePublished - Jun 1 1992

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

Cite this

Bose, D. S., Thompson, A. S., Ching, J., Hartley, J. A., Berardini, M. D., Jenkins, T. C., Neidle, S., Hurley, L. H., & Thurston, D. E. (1992). Rational Design of a Highly Efficient Irreversible DNA Interstrand Cross-Linking Agent Based on the Pyrrolobenzodiazepine Ring System. Journal of the American Chemical Society, 114(12), 4939-4941. https://doi.org/10.1021/ja00038a089