Rationale for design of biologically reversible drug derivatives: prodrugs

A. A. Sinkula, Samuel H Yalkowsky

Research output: Contribution to journalArticle

217 Citations (Scopus)
Original languageEnglish (US)
Pages (from-to)181-210
Number of pages30
JournalJournal of Pharmaceutical Sciences
Volume64
Issue number2
StatePublished - 1975
Externally publishedYes

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Delayed-Action Preparations
Sulfatases
Irritants
Gastrointestinal Diseases
Intramuscular Injections
Prodrugs
Esterases
Structure-Activity Relationship
Acid Phosphatase
Intravenous Injections
Antineoplastic Agents
Solubility
Alkaline Phosphatase
Hydrolysis
Binding Sites
Enzymes
Pharmaceutical Preparations
Odorants

ASJC Scopus subject areas

  • Molecular Medicine
  • Chemistry(all)
  • Organic Chemistry
  • Drug Discovery
  • Pharmaceutical Science
  • Pharmacology

Cite this

Rationale for design of biologically reversible drug derivatives : prodrugs. / Sinkula, A. A.; Yalkowsky, Samuel H.

In: Journal of Pharmaceutical Sciences, Vol. 64, No. 2, 1975, p. 181-210.

Research output: Contribution to journalArticle

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