Real-time gene expression tracking in a 3D tumor wounding model for gold nanorod-mediated photothermal therapy

Yuan Xiao, Reza Riahi, Pak Kin Wong

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

This paper describes a three-dimensional in vitro model of gold nanorod-mediated tumor photothermal therapy. With real-time monitoring of dynamic gene expression at the single cell level, our study revealed the dynamics of cell motility during the post-irradiation wound-healing process, and identified two distinct modes of cell healing responses induced by localized hyperthermia.

Original languageEnglish (US)
Title of host publication18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
PublisherChemical and Biological Microsystems Society
Pages766-768
Number of pages3
ISBN (Print)9780979806476
StatePublished - 2014
Event18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States
Duration: Oct 26 2014 → Oct 30 2014

Other

Other18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
CountryUnited States
CitySan Antonio
Period10/26/14 → 10/30/14

Keywords

  • 3D spheroids
  • Gold nanorods
  • Photothermal therapy
  • Single cell
  • Tumor

ASJC Scopus subject areas

  • Control and Systems Engineering

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