Recent advances in cryptosporidiosis: The immune response

Research output: Contribution to journalReview article

97 Scopus citations

Abstract

An increased understanding of host immune responses to Cryptosporidium parvum which are responsible for clearance of primary infection and resistance to reinfection, and characterization of the parasite molecules to which they are directed, are essential for discovery of effective active and passive immunization strategies against cryptosporidiosis. In this article, recent advances in knowledge of humoral and cellular immune responses to C. parvum, their antigen specificities, and mechanisms of protection are briefly reviewed.

Original languageEnglish (US)
Pages (from-to)1067-1080
Number of pages14
JournalMicrobes and Infection
Volume4
Issue number10
DOIs
StatePublished - Aug 1 2002

Keywords

  • Antigens, protozoan
  • Cryptosporidiosis/im [Immunology]
  • Cryptosporidiosis/pc [Prevention and control]
  • Cryptosporidiosis/th [Therapy]
  • Cryptosporidium parvum/im [Immunology]
  • Host-parasite relations
  • Immunity, cellular
  • Immunization, passive

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Infectious Diseases

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