Recent advances in cryptosporidiosis: The immune response

Research output: Contribution to journalArticle

97 Citations (Scopus)

Abstract

An increased understanding of host immune responses to Cryptosporidium parvum which are responsible for clearance of primary infection and resistance to reinfection, and characterization of the parasite molecules to which they are directed, are essential for discovery of effective active and passive immunization strategies against cryptosporidiosis. In this article, recent advances in knowledge of humoral and cellular immune responses to C. parvum, their antigen specificities, and mechanisms of protection are briefly reviewed.

Original languageEnglish (US)
Pages (from-to)1067-1080
Number of pages14
JournalMicrobes and Infection
Volume4
Issue number10
DOIs
StatePublished - Aug 2002

Fingerprint

Cryptosporidium parvum
Cryptosporidiosis
Passive Immunization
Humoral Immunity
Cellular Immunity
Parasites
Vaccination
Antigens
Infection

Keywords

  • Antigens, protozoan
  • Cryptosporidiosis/im [Immunology]
  • Cryptosporidiosis/pc [Prevention and control]
  • Cryptosporidiosis/th [Therapy]
  • Cryptosporidium parvum/im [Immunology]
  • Host-parasite relations
  • Immunity, cellular
  • Immunization, passive

ASJC Scopus subject areas

  • Microbiology
  • Infectious Diseases

Cite this

Recent advances in cryptosporidiosis : The immune response. / Riggs, Michael W.

In: Microbes and Infection, Vol. 4, No. 10, 08.2002, p. 1067-1080.

Research output: Contribution to journalArticle

@article{5332f356ff454aa8bf23d65923813227,
title = "Recent advances in cryptosporidiosis: The immune response",
abstract = "An increased understanding of host immune responses to Cryptosporidium parvum which are responsible for clearance of primary infection and resistance to reinfection, and characterization of the parasite molecules to which they are directed, are essential for discovery of effective active and passive immunization strategies against cryptosporidiosis. In this article, recent advances in knowledge of humoral and cellular immune responses to C. parvum, their antigen specificities, and mechanisms of protection are briefly reviewed.",
keywords = "Antigens, protozoan, Cryptosporidiosis/im [Immunology], Cryptosporidiosis/pc [Prevention and control], Cryptosporidiosis/th [Therapy], Cryptosporidium parvum/im [Immunology], Host-parasite relations, Immunity, cellular, Immunization, passive",
author = "Riggs, {Michael W}",
year = "2002",
month = "8",
doi = "10.1016/S1286-4579(02)01631-3",
language = "English (US)",
volume = "4",
pages = "1067--1080",
journal = "Microbes and Infection",
issn = "1286-4579",
publisher = "Elsevier Masson SAS",
number = "10",

}

TY - JOUR

T1 - Recent advances in cryptosporidiosis

T2 - The immune response

AU - Riggs, Michael W

PY - 2002/8

Y1 - 2002/8

N2 - An increased understanding of host immune responses to Cryptosporidium parvum which are responsible for clearance of primary infection and resistance to reinfection, and characterization of the parasite molecules to which they are directed, are essential for discovery of effective active and passive immunization strategies against cryptosporidiosis. In this article, recent advances in knowledge of humoral and cellular immune responses to C. parvum, their antigen specificities, and mechanisms of protection are briefly reviewed.

AB - An increased understanding of host immune responses to Cryptosporidium parvum which are responsible for clearance of primary infection and resistance to reinfection, and characterization of the parasite molecules to which they are directed, are essential for discovery of effective active and passive immunization strategies against cryptosporidiosis. In this article, recent advances in knowledge of humoral and cellular immune responses to C. parvum, their antigen specificities, and mechanisms of protection are briefly reviewed.

KW - Antigens, protozoan

KW - Cryptosporidiosis/im [Immunology]

KW - Cryptosporidiosis/pc [Prevention and control]

KW - Cryptosporidiosis/th [Therapy]

KW - Cryptosporidium parvum/im [Immunology]

KW - Host-parasite relations

KW - Immunity, cellular

KW - Immunization, passive

UR - http://www.scopus.com/inward/record.url?scp=0036675343&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036675343&partnerID=8YFLogxK

U2 - 10.1016/S1286-4579(02)01631-3

DO - 10.1016/S1286-4579(02)01631-3

M3 - Article

C2 - 12191657

AN - SCOPUS:0036675343

VL - 4

SP - 1067

EP - 1080

JO - Microbes and Infection

JF - Microbes and Infection

SN - 1286-4579

IS - 10

ER -