Recent advances in the metal-catalyzed ring expansions of three- and four-membered rings

Daniel J. MacK, Jon T Njardarson

Research output: Contribution to journalArticle

151 Scopus citations


New catalytic ring-expansion reactions of strained ring (hetero- and carbocyclic) substrates reported in the last six years (2006-2012) are presented. As evident from the diversity of new approaches, this is a vibrant area of research. Metals ranging from magnesium to gold have been used as catalysts. Some of these reactions allow access to enantioenriched products by employing catalysts decorated with chiral organic motifs (primarily C-2 symmetric).

Original languageEnglish (US)
Pages (from-to)272-286
Number of pages15
JournalACS Catalysis
Issue number2
Publication statusPublished - Feb 1 2013



  • catalysis
  • cyclobutane
  • cyclopropane
  • heterocycles
  • ring expansion
  • strained rings

ASJC Scopus subject areas

  • Catalysis

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