Recruitment of black subjects for a natural history study of intracerebral hemorrhage

Dorothy F. Edwards, Ravi Menon, Ali Fokar, Christopher Gibbons, Jeffrey Wing, Brisa Sanchez, Chelsea S. Kidwell

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Historically, recruitment of minority subjects for clinical research has been challenging. We developed culturally-tailored recruitment materials for a longitudinal, natural history study of intracerebral hemorrhage (ICH) and trained recruiting coordinators in cultural competence. Of 285 subjects meeting inclusion criteria, 158 (55% of those eligible) agreed to participate (60% of eligible Blacks vs. 45% of eligible non-Blacks, p=.02). Of those enrolled, 138 (87%) agreed to participate in the genetic sub-study (86% of Blacks vs. 90% of non-Blacks enrolled, p=.78). Of those subjects who refused enrollment, lack of interest in research (42%) was the most common reason given for the study as a whole. A higher rate of enrollment was achieved in Blacks vs. non-Blacks in this ICH clinical research study employing culturally tailored recruitment approaches and training of recruitment coordinators to overcome traditional recruitment barriers to research participation in minority patients.

Original languageEnglish (US)
Pages (from-to)27-35
Number of pages9
JournalJournal of health care for the poor and underserved
Volume24
Issue number1
DOIs
StatePublished - Feb 1 2013
Externally publishedYes

Keywords

  • African Americans
  • Genetics
  • Intracerebral hemorrhage
  • Research subject recruitment

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

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