Reduction in urinary arsenic with bottled-water intervention

Arun B. Josyula, Hannah McClellen, Tracy A. Hysong, Margaret Kurzius-Spencer, Gerald S. Poplin, Stefan Stürup, Jefferey L. Burgess

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

The study was conducted to measure the effectiveness of providing bottled water in reducing arsenic exposure. Urine, tap-water and toenail samples were collected from non-smoking adults residing in Ajo (n=40) and Tucson (n=33), Arizona, USA. The Ajo subjects were provided bottled water for 12 months prior to re-sampling. The mean total arsenic (μg /L) in tap-water was 20.3±3.7 in Ajo and 4.0±2.3 in Tucson. Baseline urinary total inorganic arsenic (μg/L) was significantly higher among the Ajo subjects (n=40, 29.1±20.4) than among the Tucson subjects (n=32, 11.0±12.0, p<0.00 1), as was creatinine-adjusted urinary total inorganic arsenic (μg/g) (35.5±25.2 vs 13.2±9.3, p<0.001). Baseline concentrations of arsenic (μg/g) in toenails were also higher among the Ajo subjects (0.51±0.72) than among the Tucson subjects (0.17±0.21) (p<0.001). After the intervention, the mean urinary total inorganic arsenic in Ajo (n=36) dropped by 21%, from 29.4±21.1 to 23.2±23.2 (p=0.026). The creatinine-adjusted urinary total inorganic arsenic and toenail arsenic levels did not differ significantly with the intervention. Provision of arsenic-free bottled water resulted in a modest reduction in urinary total inorganic arsenic.

Original languageEnglish (US)
Pages (from-to)298-304
Number of pages7
JournalJournal of Health, Population and Nutrition
Volume24
Issue number3
StatePublished - Sep 2006

Keywords

  • Arsenic
  • Bottled water
  • Drinking-water
  • United States

ASJC Scopus subject areas

  • Food Science
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

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    Josyula, A. B., McClellen, H., Hysong, T. A., Kurzius-Spencer, M., Poplin, G. S., Stürup, S., & Burgess, J. L. (2006). Reduction in urinary arsenic with bottled-water intervention. Journal of Health, Population and Nutrition, 24(3), 298-304.