Regioselective ring metalation in [2,4]-bisoxazoles

David R. Williams, Dawn A. Brooks, Kevin G. Meyer, Marty Pagel

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

The efficient, highly regioselective metalation of a 2,4-disubstituted bisoxazole system is described. The resulting lithio-oxazole is a competent nucleophile in subsequent alkylations.

Original languageEnglish (US)
Pages (from-to)8023-8026
Number of pages4
JournalTetrahedron Letters
Volume39
Issue number44
DOIs
StatePublished - Oct 29 1998

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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