Regular Physical Activity Levels and Incidence of Restrictive Spirometry Pattern: A Longitudinal Analysis of 2 Population-Based Cohorts

Anne Elie Carsin, Dirk Keidel, Elaine Fuertes, Medea Imboden, Joost Weyler, Dennis Nowak, Joachim Heinrich, Silvia Pascual Erquicia, Jesus Martinez-Moratalla, Ismael Huerta, Jose Luis Sanchez, Emmanuel Schaffner, Seraina Caviezel, Anna Beckmeyer-Borowko, Chantal Raherison, Isabelle Pin, Pascal Demoly, Bénédicte Leynaert, Isa Cerveri, Giulia SquillaciotiSimone Accordini, Thorarinn Gislason, Cecilie Svanes, Kjell Toren, Bertill Forsberg, Christer Janson, Rain Jogi, Margareta Emtner, Francisco Gómez Real, Debbie Jarvis, Stefano Guerra, Shyamali C. Dharmage, Nicole Probst-Hensch, Judith Garcia-Aymerich

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

We estimated the association between regular physical activity and the incidence of restrictive spirometry pattern. Forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), and physical activity were assessed in 2 population-based European cohorts (European Community Respiratory Health Survey: n = 2,757, aged 39-67 years; and Swiss Study on Air Pollution and Lung and Heart Diseases in Adults: n = 2,610, aged 36-82 years) first in 2000-2002 and again approximately 10 years later (2010-2013). Subjects with restrictive or obstructive spirometry pattern at baseline were excluded. We assessed the association of being active at baseline (defined as being physically active at least 2-3 times/week for ≥1 hour) with restrictive spirometry pattern at follow-up (defined as a postbronchodilation FEV1/FVC ratio of at least the lower limit of normal and FVC of <80% predicted) using modified Poisson regression, adjusting for relevant confounders. After 10 years of follow-up, 3.3% of participants had developed restrictive spirometry pattern. Being physically active was associated with a lower risk of developing this phenotype (relative risk = 0.76, 95% confidence interval: 0.59, 0.98). This association was stronger among those who were overweight and obese than among those of normal weight (P for interaction = 0.06). In 2 large European studies, adults practicing regular physical activity were at lower risk of developing restrictive spirometry pattern over 10 years.

Original languageEnglish (US)
Pages (from-to)1521-1528
Number of pages8
JournalAmerican journal of epidemiology
Volume189
Issue number12
DOIs
StatePublished - Dec 1 2020
Externally publishedYes

Keywords

  • BMI
  • FVC
  • physical activity
  • restrictive spirometry
  • spirometry

ASJC Scopus subject areas

  • Epidemiology

Fingerprint

Dive into the research topics of 'Regular Physical Activity Levels and Incidence of Restrictive Spirometry Pattern: A Longitudinal Analysis of 2 Population-Based Cohorts'. Together they form a unique fingerprint.

Cite this