Regulation of isotype switching

Donata Vercelli, Raif S. Geha

Research output: Contribution to journalArticle

54 Scopus citations

Abstract

In the past year, our understanding of the mechanisms that regulate isotype switching has significantly progressed. Activation of germ line transcription by isotype-specific cytokines is emerging as a crucial mechanism for increasing the accessibility of a particular switch region, and targeting switch recombination.

Original languageEnglish (US)
Pages (from-to)794-797
Number of pages4
JournalCurrent Opinion in Immunology
Volume4
Issue number6
DOIs
StatePublished - Dec 1992
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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