Relationship of parental smoking to wheezing and nonwheezing lower respiratory tract illnesses in infancy

Anne L Wright, Catharine Holberg, Fernando Martinez, Lynn M. Taussig

Research output: Contribution to journalArticle

140 Citations (Scopus)

Abstract

The relationship between parental smoking and lower respiratory tract illness (LRI) was studied in a large cohort of infants followed prospectively from birth. illnesses were diagnosed by physicians using agreed-on criteria, and parental smoking histories were obtained by questionnaire. The LRIs were differentiated into wheezing and nonwheezing episodes, and the age at first illness of either type was evaluated in relation to smoking by parents. The odds of having an LRI were significantly higher in children whose mothers smoked (odds ratio 1.52; confidence interval 1.07 to 2.15). The odds were higher if the mother smoked a pack of cigarettes or more per day and if the child stayed home rather than attending day care (odds ratio 2.8; confidence interval 1.43 to 5.5). Logistic regression indicated that the LRI rate was significantly elevated both in children exposed to heavy maternal smoke in the absence of day care, and in those who use day care but were not exposed to maternal smoking of a pack or more per day. These findings could nor be attributed to other confounding variables. Nelther paternal smoking nor smoking by other household members was consistently related to the LRI rate. The relationship of maternal smoking to LRI rate was evident for both wheezing and nonwheezing illnesses. Maternal smoking of a pack or more per day was also related to an early age at first LRI, for both wheezing (p<0.05) and nonwheezing (p<0.002) illnesses. In sum, maternal smoking is associated with a higher rate of LRIs in the first year, particularly when mothers smoked a pack or more per day and when the child did not use day care.

Original languageEnglish (US)
Pages (from-to)207-214
Number of pages8
JournalThe Journal of Pediatrics
Volume118
Issue number2
DOIs
StatePublished - 1991

Fingerprint

Respiratory Sounds
Respiratory System
Smoking
Mothers
Odds Ratio
Confidence Intervals
Confounding Factors (Epidemiology)
Smoke
Tobacco Products
Parents
Logistic Models
Parturition
Physicians

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Relationship of parental smoking to wheezing and nonwheezing lower respiratory tract illnesses in infancy. / Wright, Anne L; Holberg, Catharine; Martinez, Fernando; Taussig, Lynn M.

In: The Journal of Pediatrics, Vol. 118, No. 2, 1991, p. 207-214.

Research output: Contribution to journalArticle

@article{e0624d597c3e43acb7b2fe59482e84d9,
title = "Relationship of parental smoking to wheezing and nonwheezing lower respiratory tract illnesses in infancy",
abstract = "The relationship between parental smoking and lower respiratory tract illness (LRI) was studied in a large cohort of infants followed prospectively from birth. illnesses were diagnosed by physicians using agreed-on criteria, and parental smoking histories were obtained by questionnaire. The LRIs were differentiated into wheezing and nonwheezing episodes, and the age at first illness of either type was evaluated in relation to smoking by parents. The odds of having an LRI were significantly higher in children whose mothers smoked (odds ratio 1.52; confidence interval 1.07 to 2.15). The odds were higher if the mother smoked a pack of cigarettes or more per day and if the child stayed home rather than attending day care (odds ratio 2.8; confidence interval 1.43 to 5.5). Logistic regression indicated that the LRI rate was significantly elevated both in children exposed to heavy maternal smoke in the absence of day care, and in those who use day care but were not exposed to maternal smoking of a pack or more per day. These findings could nor be attributed to other confounding variables. Nelther paternal smoking nor smoking by other household members was consistently related to the LRI rate. The relationship of maternal smoking to LRI rate was evident for both wheezing and nonwheezing illnesses. Maternal smoking of a pack or more per day was also related to an early age at first LRI, for both wheezing (p<0.05) and nonwheezing (p<0.002) illnesses. In sum, maternal smoking is associated with a higher rate of LRIs in the first year, particularly when mothers smoked a pack or more per day and when the child did not use day care.",
author = "Wright, {Anne L} and Catharine Holberg and Fernando Martinez and Taussig, {Lynn M.}",
year = "1991",
doi = "10.1016/S0022-3476(05)80484-6",
language = "English (US)",
volume = "118",
pages = "207--214",
journal = "Journal of Pediatrics",
issn = "0022-3476",
publisher = "Mosby Inc.",
number = "2",

}

TY - JOUR

T1 - Relationship of parental smoking to wheezing and nonwheezing lower respiratory tract illnesses in infancy

AU - Wright, Anne L

AU - Holberg, Catharine

AU - Martinez, Fernando

AU - Taussig, Lynn M.

PY - 1991

Y1 - 1991

N2 - The relationship between parental smoking and lower respiratory tract illness (LRI) was studied in a large cohort of infants followed prospectively from birth. illnesses were diagnosed by physicians using agreed-on criteria, and parental smoking histories were obtained by questionnaire. The LRIs were differentiated into wheezing and nonwheezing episodes, and the age at first illness of either type was evaluated in relation to smoking by parents. The odds of having an LRI were significantly higher in children whose mothers smoked (odds ratio 1.52; confidence interval 1.07 to 2.15). The odds were higher if the mother smoked a pack of cigarettes or more per day and if the child stayed home rather than attending day care (odds ratio 2.8; confidence interval 1.43 to 5.5). Logistic regression indicated that the LRI rate was significantly elevated both in children exposed to heavy maternal smoke in the absence of day care, and in those who use day care but were not exposed to maternal smoking of a pack or more per day. These findings could nor be attributed to other confounding variables. Nelther paternal smoking nor smoking by other household members was consistently related to the LRI rate. The relationship of maternal smoking to LRI rate was evident for both wheezing and nonwheezing illnesses. Maternal smoking of a pack or more per day was also related to an early age at first LRI, for both wheezing (p<0.05) and nonwheezing (p<0.002) illnesses. In sum, maternal smoking is associated with a higher rate of LRIs in the first year, particularly when mothers smoked a pack or more per day and when the child did not use day care.

AB - The relationship between parental smoking and lower respiratory tract illness (LRI) was studied in a large cohort of infants followed prospectively from birth. illnesses were diagnosed by physicians using agreed-on criteria, and parental smoking histories were obtained by questionnaire. The LRIs were differentiated into wheezing and nonwheezing episodes, and the age at first illness of either type was evaluated in relation to smoking by parents. The odds of having an LRI were significantly higher in children whose mothers smoked (odds ratio 1.52; confidence interval 1.07 to 2.15). The odds were higher if the mother smoked a pack of cigarettes or more per day and if the child stayed home rather than attending day care (odds ratio 2.8; confidence interval 1.43 to 5.5). Logistic regression indicated that the LRI rate was significantly elevated both in children exposed to heavy maternal smoke in the absence of day care, and in those who use day care but were not exposed to maternal smoking of a pack or more per day. These findings could nor be attributed to other confounding variables. Nelther paternal smoking nor smoking by other household members was consistently related to the LRI rate. The relationship of maternal smoking to LRI rate was evident for both wheezing and nonwheezing illnesses. Maternal smoking of a pack or more per day was also related to an early age at first LRI, for both wheezing (p<0.05) and nonwheezing (p<0.002) illnesses. In sum, maternal smoking is associated with a higher rate of LRIs in the first year, particularly when mothers smoked a pack or more per day and when the child did not use day care.

UR - http://www.scopus.com/inward/record.url?scp=0026015949&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026015949&partnerID=8YFLogxK

U2 - 10.1016/S0022-3476(05)80484-6

DO - 10.1016/S0022-3476(05)80484-6

M3 - Article

C2 - 1993946

AN - SCOPUS:0026015949

VL - 118

SP - 207

EP - 214

JO - Journal of Pediatrics

JF - Journal of Pediatrics

SN - 0022-3476

IS - 2

ER -