Reticulocytopenic, Coombs' positive anemia induced by procainamide

Ronald B Schifman, H. Garewal, D. Shillington

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A case of Coombs' positive anemia in a man who had procainamide-induced lupus erythematosus syndrome is reported. The patient had a hemoglobin of 4.3 gm/dl and reticulocytopenia (3.1% corrected). Serum lactate dehydrogenase and haptoglobin levels were normal, and total bilirubin was only slightly elevated. Two other reported cases of procainamide-induced hemolytic anemia have demonstrated similar findings. Apparently, procainamide occasionally may induce a reversible, reticulocytopenic, Coombs' positive anemia that is not associated with laboratory evidence of acute hemolysis.

Original languageEnglish (US)
Pages (from-to)66-68
Number of pages3
JournalAmerican Journal of Clinical Pathology
Volume80
Issue number1
StatePublished - 1983

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Procainamide
Anemia
Haptoglobins
Hemolytic Anemia
Hemolysis
L-Lactate Dehydrogenase
Bilirubin
Hemoglobins
Serum

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Reticulocytopenic, Coombs' positive anemia induced by procainamide. / Schifman, Ronald B; Garewal, H.; Shillington, D.

In: American Journal of Clinical Pathology, Vol. 80, No. 1, 1983, p. 66-68.

Research output: Contribution to journalArticle

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