State-of-the-art array detector technology is having a profound impact on numerous types of chemical analysis. The unique capabilities of these detectors create unprecedented opportunities in the various domains of high resolution, ultra sensitive optical spectroscopy. These array detectors, including charge coupled devices (CCDs) and charge injection devices (CIDs) have found successful application in molecular fluorescence, chemiluminescence, and atomic emission spectroscopies. The potential of these detectors for spatial and spectral imaging has been realized in a variety of applications including thin layer chromatography and flow cytometry. Applications of array detectors to these areas are discussed along with the inherently unique methods of operation such as random access integration, time delay integration, and flat fielding.