Reye's syndrome in the adult

Case report and review of the literature

A. Stillman, H. Gitter, Richard E Sobonya, R. Sobonya, C. M. Payne, D. Ettinger, S. M. Lee

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

A 22-year-old male presented with a brief history of progressive encephalopathy. One week previously, he had developed an upper respiratory infection that resolved spontaneously and was followed by intractable vomiting. He had taken salicylates for several days during the viral syndrome. The diagnosis of Reye's syndrome was confirmed by hepatic histology. Aggressive conservative management was followed by complete metabolic and neurological rcovery. There are fewer than 10 reported cases of Reye's syndrome in adults but this disease may be more common than is generally suspected. The diagnosis should be considered in patients presenting with emesis and obtundation, who have recently had a viral illness and exhibit elevated blood ammonia and transaminases with normal cerebrospinal fluid. Confirmation is achieved by liver biopsy. Therapy is directed toward aggressive reduction of increased intracranial pressure.

Original languageEnglish (US)
Pages (from-to)365-368
Number of pages4
JournalAmerican Journal of Gastroenterology
Volume78
Issue number6
StatePublished - 1983

Fingerprint

Reye Syndrome
Vomiting
Salicylates
Liver
Intracranial Pressure
Brain Diseases
Transaminases
Ammonia
Respiratory Tract Infections
Cerebrospinal Fluid
Histology
Biopsy
Therapeutics
Conservative Treatment

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Stillman, A., Gitter, H., Sobonya, R. E., Sobonya, R., Payne, C. M., Ettinger, D., & Lee, S. M. (1983). Reye's syndrome in the adult: Case report and review of the literature. American Journal of Gastroenterology, 78(6), 365-368.

Reye's syndrome in the adult : Case report and review of the literature. / Stillman, A.; Gitter, H.; Sobonya, Richard E; Sobonya, R.; Payne, C. M.; Ettinger, D.; Lee, S. M.

In: American Journal of Gastroenterology, Vol. 78, No. 6, 1983, p. 365-368.

Research output: Contribution to journalArticle

Stillman, A, Gitter, H, Sobonya, RE, Sobonya, R, Payne, CM, Ettinger, D & Lee, SM 1983, 'Reye's syndrome in the adult: Case report and review of the literature', American Journal of Gastroenterology, vol. 78, no. 6, pp. 365-368.
Stillman A, Gitter H, Sobonya RE, Sobonya R, Payne CM, Ettinger D et al. Reye's syndrome in the adult: Case report and review of the literature. American Journal of Gastroenterology. 1983;78(6):365-368.
Stillman, A. ; Gitter, H. ; Sobonya, Richard E ; Sobonya, R. ; Payne, C. M. ; Ettinger, D. ; Lee, S. M. / Reye's syndrome in the adult : Case report and review of the literature. In: American Journal of Gastroenterology. 1983 ; Vol. 78, No. 6. pp. 365-368.
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