Risk factors for disseminated coccidioidomycosis, United States

Camila D. Odio, Beatriz E. Marciano, John N Galgiani, Steven M. Holland

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Of 150,000 new coccidioidomycosis infections that occur annually in the United States, ≈1% disseminate; one third of those cases are fatal. Immunocompromised hosts have higher rates of dissemination. We identified 8 patients with disseminated coccidioidomycosis who had defects in the interleukin-12/interferon-γ and STAT3 axes, indicating that these are critical host defense pathways.

Original languageEnglish (US)
Pages (from-to)308-311
Number of pages4
JournalEmerging Infectious Diseases
Volume23
Issue number2
DOIs
StatePublished - Feb 1 2017

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Coccidioidomycosis
Immunocompromised Host
Interleukin-12
Interferons
Infection

ASJC Scopus subject areas

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

Cite this

Risk factors for disseminated coccidioidomycosis, United States. / Odio, Camila D.; Marciano, Beatriz E.; Galgiani, John N; Holland, Steven M.

In: Emerging Infectious Diseases, Vol. 23, No. 2, 01.02.2017, p. 308-311.

Research output: Contribution to journalArticle

Odio, Camila D. ; Marciano, Beatriz E. ; Galgiani, John N ; Holland, Steven M. / Risk factors for disseminated coccidioidomycosis, United States. In: Emerging Infectious Diseases. 2017 ; Vol. 23, No. 2. pp. 308-311.
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