Risk of Atrial Fibrillation and Bleeding Diathesis Associated With Ibrutinib Treatment: A Systematic Review and Pooled Analysis of Four Randomized Controlled Trials

Seongseok Yun, Nicole D. Vincelette, Utkarsh Acharya, Ivo L Abraham

Research output: Contribution to journalArticle

42 Scopus citations

Abstract

Micro-Abstract The goal of the present study was to precisely assess the risk of atrial fibrillation/flutter (Afib/Aflutter) and bleeding associated with ibrutinib compared to other treatments. The risks of Afib/Aflutter and all-grade bleeding were significantly higher in the ibrutinib group.

Original languageEnglish (US)
Pages (from-to)31-37.e13
JournalClinical Lymphoma, Myeloma and Leukemia
Volume17
Issue number1
DOIs
StatePublished - Jan 1 2017

Keywords

  • Anticoagulation
  • Atrial flutter
  • Chronic lymphocytic leukemia
  • Mantle cell lymphoma
  • Waldenstrom macroglobulinemia

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

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