Robust local explanations for healthcare predictive analytics: An application to fragility fracture risk modeling

Buomsoo Kim, Karthik Srinivasan, Sudha Ram

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

With recent advancements in data analytics, healthcare predictive analytics (HPA) is garnering growing interest among practitioners and researchers. However, it is risky to blindly accept the results and users will not accept the HPA model if transparency is not guaranteed. To address this challenge, we propose the RObust Local EXplanations (ROLEX) method, which provides robust, instance-level explanations for any HPA model. The applicability of the ROLEX method is demonstrated using the fragility fracture prediction problem. Analysis with a large real-world dataset demonstrates that our method outperforms state-of-the-art methods in terms of local fidelity. The ROLEX method is applicable to various types of HPA problems beyond the fragility fracture problem. It is applicable to any type of supervised learning model and provides fine-grained explanations that can improve understanding of the phenomenon of interest. Finally, we discuss theoretical implications of our study in light of healthcare IS, big data, and design science.

Original languageEnglish (US)
Title of host publication40th International Conference on Information Systems, ICIS 2019
PublisherAssociation for Information Systems
ISBN (Electronic)9780996683197
StatePublished - 2020
Event40th International Conference on Information Systems, ICIS 2019 - Munich, Germany
Duration: Dec 15 2019Dec 18 2019

Publication series

Name40th International Conference on Information Systems, ICIS 2019

Conference

Conference40th International Conference on Information Systems, ICIS 2019
CountryGermany
CityMunich
Period12/15/1912/18/19

Keywords

  • Explainable artificial intelligence
  • Fragility fracture
  • Healthcare predictive analytics

ASJC Scopus subject areas

  • Computer Science Applications
  • Information Systems

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