The stability of the infectivity of Simian rotavirus, SAII, has been analysed and compared to the stability of reovirus type I. SAII infectivity was stable to freeze-thawing, sonication, incubation at 25°C overnight or at 37°C for 1 h and to treatment with acid, ether, chloroform and Genetron. In contrast to reovirus, the infectivity of SAII was more rapidly inactivated by heating at 50°C. SAII infectivity was inactivated above pH 10.0 and by heating at 50°C in 2 M-MgCl2, but was stabilized by heating in 2 M-MgSO4; reovirus I infectivity was enhanced by heating in MgCl2. Both SAII and reovirus I were inactivated by freezing in MgCl2. These results show that rotaviruses and reoviruses can be distinguished by their patterns of inactivation by physical and chemical agents.
|Original language||English (US)|
|Number of pages||7|
|Journal||Journal of General Virology|
|State||Published - Dec 1 1979|
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