Abstract
The stability of the infectivity of Simian rotavirus, SAII, has been analysed and compared to the stability of reovirus type I. SAII infectivity was stable to freeze-thawing, sonication, incubation at 25°C overnight or at 37°C for 1 h and to treatment with acid, ether, chloroform and Genetron. In contrast to reovirus, the infectivity of SAII was more rapidly inactivated by heating at 50°C. SAII infectivity was inactivated above pH 10.0 and by heating at 50°C in 2 M-MgCl2, but was stabilized by heating in 2 M-MgSO4; reovirus I infectivity was enhanced by heating in MgCl2. Both SAII and reovirus I were inactivated by freezing in MgCl2. These results show that rotaviruses and reoviruses can be distinguished by their patterns of inactivation by physical and chemical agents.
Original language | English (US) |
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Pages (from-to) | 403-409 |
Number of pages | 7 |
Journal | Journal of General Virology |
Volume | 43 |
Issue number | 2 |
State | Published - Dec 1 1979 |
Externally published | Yes |
ASJC Scopus subject areas
- Virology