Safe, rapid administration schedule for cis-platinum - Mannitol

J. M. Rainey, David S Alberts

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Cis-diamminedichloroplatinum (II) cis-platinum, 25-75 mg/m2, with 40 gm mannitol and fluid were given over 1-2 hours to 40 patients with no evidence of elevated serum creatinine levels. Cis-platinum was administered every 28 days at a dose of 50 mg/m2 to 22 patients, and 75 mg/m2 to 6 patients. Patients received from one to eight courses of therapy with no change in their serum creatinine level. A safe, simple method of cis-platinum administration has been achieved.

Original languageEnglish (US)
Pages (from-to)371-375
Number of pages5
JournalMedical and Pediatric Oncology
Volume4
Issue number14
StatePublished - 1978

Fingerprint

Mannitol
Cisplatin
Appointments and Schedules
Creatinine
Serum
Therapeutics

ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Pediatrics, Perinatology, and Child Health

Cite this

Safe, rapid administration schedule for cis-platinum - Mannitol. / Rainey, J. M.; Alberts, David S.

In: Medical and Pediatric Oncology, Vol. 4, No. 14, 1978, p. 371-375.

Research output: Contribution to journalArticle

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