SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2

Yuyang Lei, Jiao Zhang, Cara R. Schiavon, Ming He, Lili Chen, Hui Shen, Yichi Zhang, Qian Yin, Yoshitake Cho, Leonardo Andrade, Gerald S. Shadel, Mark Hepokoski, Ting Lei, Hongliang Wang, Jin Zhang, Jason X.J. Yuan, Atul Malhotra, Uri Manor, Shengpeng Wang, Zu Yi YuanJohn Y.J. Shyy

Research output: Contribution to journalLetterpeer-review

2 Scopus citations
Original languageEnglish (US)
Pages (from-to)1323-1326
Number of pages4
JournalCirculation research
DOIs
StateAccepted/In press - 2021
Externally publishedYes

Keywords

  • angiotensin-converting enzyme 2
  • endothelium
  • SARS-CoV-2

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

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