Scaling analysis of a universal electrode for molecular biosensors

Mandy L Y Sin, Victor U. Constantino, Vincent Gau, David A. Haake, Pak Kin Wong

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Nanoscale and molecular manipulation techniques, such as concentration, are crucial for the success of an automated point-of-care diagnostic system. Here, we report the development of an electrokinetic concentrator for integrated bioanalytical systems. By combining different electrokinetic forces, the concentrator is capable of concentrating nanoscale particles in less than 1 min and increasing the concentration by 2 orders of magnitude. The concentrator used a universal electrode design developed for a versatile electrochemical sensor platform. We performed a scaling analysis to generalize and optimize the design of the universal electrode. The data collapse analysis showed that the concentration process follows a universal kinetics, and the time scaling factor (7) scales with the effective electric field (E) as T ∼ e 0.48±.05 while the intensity scaling factor (I) increases with the effective electric field (E) as I ∼E0.93±0.1.2.

Original languageEnglish (US)
Title of host publication3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS
Pages1151-1155
Number of pages5
DOIs
StatePublished - 2008
Event3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2008 - Sanya, China
Duration: Jan 6 2008Jan 9 2008

Other

Other3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2008
CountryChina
CitySanya
Period1/6/081/9/08

Fingerprint

Biosensors
Electric fields
Electrochemical sensors
Electrodes
Kinetics

Keywords

  • Biosensor
  • Electrokinetic concentrator
  • Lab-on-a-chip
  • Molecular manipulation

ASJC Scopus subject areas

  • Control and Systems Engineering
  • Electrical and Electronic Engineering

Cite this

Sin, M. L. Y., Constantino, V. U., Gau, V., Haake, D. A., & Wong, P. K. (2008). Scaling analysis of a universal electrode for molecular biosensors. In 3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS (pp. 1151-1155). [4484521] https://doi.org/10.1109/NEMS.2008.4484521

Scaling analysis of a universal electrode for molecular biosensors. / Sin, Mandy L Y; Constantino, Victor U.; Gau, Vincent; Haake, David A.; Wong, Pak Kin.

3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS. 2008. p. 1151-1155 4484521.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Sin, MLY, Constantino, VU, Gau, V, Haake, DA & Wong, PK 2008, Scaling analysis of a universal electrode for molecular biosensors. in 3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS., 4484521, pp. 1151-1155, 3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2008, Sanya, China, 1/6/08. https://doi.org/10.1109/NEMS.2008.4484521
Sin MLY, Constantino VU, Gau V, Haake DA, Wong PK. Scaling analysis of a universal electrode for molecular biosensors. In 3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS. 2008. p. 1151-1155. 4484521 https://doi.org/10.1109/NEMS.2008.4484521
Sin, Mandy L Y ; Constantino, Victor U. ; Gau, Vincent ; Haake, David A. ; Wong, Pak Kin. / Scaling analysis of a universal electrode for molecular biosensors. 3rd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS. 2008. pp. 1151-1155
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