Scanning tunneling microscopy of microtubules

Stuart Hameroff, Yovana Simic-Krstic, Djuro Koruga, Murray Kelley, Robert McCuskey, Margaret Krasovich, Conrad Schneiker

Research output: Contribution to journalConference article

Abstract

Scanning tunneling microscopy (STM) was used to image neuronal microtubules, protein polymers which may be capable of information processing. Isolated microtubules fixed in 0.1% glutaraldehyde in reassembly buffer containing 0.8 M glycerol were imaged in air on a graphite substrate. STM probing showed structures approximately 25 nm inwidth, consisting of longitudinal filaments of about 4 nm width. These images match electron micrographs of microtubules and their component protofilaments.

Original languageEnglish (US)
Pages (from-to)1350-1351
Number of pages2
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume11 pt 4
StatePublished - Dec 1 1989
EventImages of the Twenty-First Century - Proceedings of the 11th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Part 2 - Seattle, WA, USA
Duration: Nov 9 1989Nov 12 1989

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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  • Cite this

    Hameroff, S., Simic-Krstic, Y., Koruga, D., Kelley, M., McCuskey, R., Krasovich, M., & Schneiker, C. (1989). Scanning tunneling microscopy of microtubules. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, 11 pt 4, 1350-1351.