Scanning tunneling microscopy of microtubules

Stuart R Hameroff, Yovana Simic-Krstic, Djuro Koruga, Murray Kelley, Robert McCuskey, Margaret Krasovich, Conrad Schneiker

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Scanning tunneling microscopy (STM) was used to image neuronal microtubules, protein polymers which may be capable of information processing. Isolated microtubules fixed in 0.1% glutaraldehyde in reassembly buffer containing 0.8 M glycerol were imaged in air on a graphite substrate. STM probing showed structures approximately 25 nm inwidth, consisting of longitudinal filaments of about 4 nm width. These images match electron micrographs of microtubules and their component protofilaments.

Original languageEnglish (US)
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
PublisherPubl by Alliance for Engineering in Medicine & Biology
Pages1350-1351
Number of pages2
Volume11 pt 4
StatePublished - 1989
EventImages of the Twenty-First Century - Proceedings of the 11th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Part 2 - Seattle, WA, USA
Duration: Nov 9 1989Nov 12 1989

Other

OtherImages of the Twenty-First Century - Proceedings of the 11th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Part 2
CitySeattle, WA, USA
Period11/9/8911/12/89

Fingerprint

Scanning tunneling microscopy
Microtubule Proteins
Graphite
Glutaral
Glycerol
Buffers
Polymers
Proteins
Electrons
Substrates
Air

ASJC Scopus subject areas

  • Bioengineering
  • Engineering(all)

Cite this

Hameroff, S. R., Simic-Krstic, Y., Koruga, D., Kelley, M., McCuskey, R., Krasovich, M., & Schneiker, C. (1989). Scanning tunneling microscopy of microtubules. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (Vol. 11 pt 4, pp. 1350-1351). Publ by Alliance for Engineering in Medicine & Biology.

Scanning tunneling microscopy of microtubules. / Hameroff, Stuart R; Simic-Krstic, Yovana; Koruga, Djuro; Kelley, Murray; McCuskey, Robert; Krasovich, Margaret; Schneiker, Conrad.

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 11 pt 4 Publ by Alliance for Engineering in Medicine & Biology, 1989. p. 1350-1351.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hameroff, SR, Simic-Krstic, Y, Koruga, D, Kelley, M, McCuskey, R, Krasovich, M & Schneiker, C 1989, Scanning tunneling microscopy of microtubules. in Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. vol. 11 pt 4, Publ by Alliance for Engineering in Medicine & Biology, pp. 1350-1351, Images of the Twenty-First Century - Proceedings of the 11th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Part 2, Seattle, WA, USA, 11/9/89.
Hameroff SR, Simic-Krstic Y, Koruga D, Kelley M, McCuskey R, Krasovich M et al. Scanning tunneling microscopy of microtubules. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 11 pt 4. Publ by Alliance for Engineering in Medicine & Biology. 1989. p. 1350-1351
Hameroff, Stuart R ; Simic-Krstic, Yovana ; Koruga, Djuro ; Kelley, Murray ; McCuskey, Robert ; Krasovich, Margaret ; Schneiker, Conrad. / Scanning tunneling microscopy of microtubules. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 11 pt 4 Publ by Alliance for Engineering in Medicine & Biology, 1989. pp. 1350-1351
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