Scattering properties of ultrafast laser-induced refractive index shaping lenticular structures in hydrogels

Kaitlin T. Wozniak, Thomas A. Germer, Sam C. Butler, Daniel R. Brooks, Krystel R. Huxlin, Jonathan D. Ellis

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

We present measurements of light scatter induced by a new ultrafast laser technique being developed for laser refractive correction in transparent ophthalmic materials such as cornea, contact lenses, and/or intraocular lenses. In this new technique, called intra-tissue refractive index shaping (IRIS), a 405 nm femtosecond laser is focused and scanned below the corneal surface, inducing a spatially-varying refractive index change that corrects vision errors. In contrast with traditional laser correction techniques, such as laser in-situ keratomileusis (LASIK) or photorefractive keratectomy (PRK), IRIS does not operate via photoablation, but rather changes the refractive index of transparent materials such as cornea and hydrogels. A concern with any laser eye correction technique is additional scatter induced by the process, which can adversely affect vision, especially at night. The goal of this investigation is to identify sources of scatter induced by IRIS and to mitigate possible effects on visual performance in ophthalmic applications. Preliminary light scattering measurements on patterns written into hydrogel showed four sources of scatter, differentiated by distinct behaviors: (1) scattering from scanned lines; (2) scattering from stitching errors, resulting from adjacent scanning fields not being aligned to one another; (3) diffraction from Fresnel zone discontinuities; and (4) long-period variations in the scans that created distinct diffraction peaks, likely due to inconsistent line spacing in the writing instrument. By knowing the nature of these different scattering errors, it will now be possible to modify and optimize the design of IRIS structures to mitigate potential deficits in visual performance in human clinical trials.

Original languageEnglish (US)
Title of host publicationFrontiers in Ultrafast Optics
Subtitle of host publicationBiomedical, Scientific, and Industrial Applications XVIII
EditorsPeter R. Herman, Michel Meunier, Roberto Osellame
PublisherSPIE
ISBN (Electronic)9781510615298
DOIs
StatePublished - Jan 1 2018
EventFrontiers in Ultrafast Optics: Biomedical, Scientific, and Industrial Applications XVIII 2018 - San Francisco, United States
Duration: Jan 28 2018Jan 30 2018

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume10522
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Conference

ConferenceFrontiers in Ultrafast Optics: Biomedical, Scientific, and Industrial Applications XVIII 2018
CountryUnited States
CitySan Francisco
Period1/28/181/30/18

Keywords

  • Diffraction
  • Femtosecond
  • Ophthalmic hydrogel
  • Photo-modification
  • Scatter
  • Vision correction

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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