Scheimpflug Corneal Densitometry Changes After the Intrastromal Corneal Ring Segment Implantation

Mohammad Reza Sedaghat, Hamed Momeni-Moghaddam, Javad Heravian, Michael W. Belin, Renato Ambrósio, Tayebe Gheysari-Alishahi, Seyyed Hossein Ghavami

Research output: Contribution to journalArticle

Abstract

PURPOSE: To investigate the changes in corneal backward scattering using Scheimpflug tomography (densitometry) 6 months after intrastromal corneal ring segments (Keraring) implant for keratoconus and to correlate with clinical results. METHODS: Along with standard ophthalmic examination, Scheimpflug tomography using Pentacam HR was performed to document corneal densitometry and corneal shape. A densitometry map was displayed using grayscale units (GSUs) ranging from 0 to 100 (minimum to maximum light scattering) in 4 concentric annuluses: central 2-, 2- to 6-, 6- to 10-, 10- to 12-, and total 12-mm corneal diameter and at 3 different depths: anterior 120 μm, posterior 60 μm, middle (varying accordingly to the total thickness), and total thickness. RESULTS: The changes in mean corneal densitometry values for anterior, central, and posterior layers were 3.82 ± 3.13, 2.70 ± 1.78, and 1.68 ± 1.52 GSU, respectively, and for annuluses of 0 to 2, 2 to 6, 6 to 10, and 10 to 12 mm were 2.96 ± 2.60, 4.53 ± 2.28, 2.09 ± 1.74, and 0.45 ± 3.93 GSU, respectively. The mean values increased for all corneal layers (P < 0.05), except in the peripheral 10- to 12-mm annulus (P> 0.05). The highest increase was in the annulus 2 to 6 mm of the anterior layer (5.72 ± 3.70 GSU). Changes in the mean densitometry showed a significant correlation with the mean of average keratometry changes only for the front corneal surface and changes in the Q-values for both corneal surfaces in the 2- to 6-mm annulus for all layers. CONCLUSIONS: Significant increase in the corneal densitometry mainly in the anterior 2- to 6-mm annulus of the cornea is associated with the position of the ring segment implant. More studies are needed to elucidate the relevance of such findings.

Original languageEnglish (US)
Pages (from-to)761-768
Number of pages8
JournalCornea
Volume39
Issue number6
DOIs
StatePublished - Jun 1 2020

ASJC Scopus subject areas

  • Ophthalmology

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    Sedaghat, M. R., Momeni-Moghaddam, H., Heravian, J., Belin, M. W., Ambrósio, R., Gheysari-Alishahi, T., & Ghavami, S. H. (2020). Scheimpflug Corneal Densitometry Changes After the Intrastromal Corneal Ring Segment Implantation. Cornea, 39(6), 761-768. https://doi.org/10.1097/ICO.0000000000002307