Science to practice: How can cardiac MR imaging help guide development of gene therapy for treatment of coronary heart disease?

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Abstract

Jacquier et al have shown with magnetic resonance (MR) imaging that therapy with direct intracardiac injection of vascular endothelial growth factor gene (VEGF) improves myocardial function in a model of myocardial infarction in swine. Jacquier and colleagues used MR imaging to measure left ventricular (LV) function and strain and showed that animals treated with gene therapy had stable ejection fraction whereas control animals deteriorated.

Original languageEnglish (US)
Pages (from-to)1-2
Number of pages2
JournalRadiology
Volume245
Issue number1
DOIs
Publication statusPublished - Oct 2007

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ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

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