Scientific and clinical basis of immunotherapy for solid tumors

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

During the last 30 yr, the principles of cancer immunology and tumor immunology have been well established. Cancers in man have been shown to have tumor associated antigens which can induce immune responses in the tumor bearing patient. In addition, immunocompetence and prognosis in cancer have clearly been related and the association of immunological deficiency with rapidly progressing cancer has been documented. Conventional surgical and radiotherapeutic approaches to cancer have either reached or are close to their limits and provide only local control for this frequently systemic disease. Systemic chemotherapy offers promising leads but as yet is only palliative in the majority of patients with cancer. This opens the opportunity for immunotherapeutic approaches based on the presence of tumor antigens and tumor specific immune responses. A number of approaches to immunotherapy have been developed in animal systems and are now being applied to man.

Original languageEnglish (US)
Title of host publicationSouth African Cancer Bulletin
Pages93-99
Number of pages7
Volume18
Edition3
StatePublished - 1974
Externally publishedYes

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Immunotherapy
Neoplasms
Neoplasm Antigens
Allergy and Immunology
Immunocompetence
Drug Therapy

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Hersh, E. M. (1974). Scientific and clinical basis of immunotherapy for solid tumors. In South African Cancer Bulletin (3 ed., Vol. 18, pp. 93-99)

Scientific and clinical basis of immunotherapy for solid tumors. / Hersh, Evan M.

South African Cancer Bulletin. Vol. 18 3. ed. 1974. p. 93-99.

Research output: Chapter in Book/Report/Conference proceedingChapter

Hersh, EM 1974, Scientific and clinical basis of immunotherapy for solid tumors. in South African Cancer Bulletin. 3 edn, vol. 18, pp. 93-99.
Hersh EM. Scientific and clinical basis of immunotherapy for solid tumors. In South African Cancer Bulletin. 3 ed. Vol. 18. 1974. p. 93-99
Hersh, Evan M. / Scientific and clinical basis of immunotherapy for solid tumors. South African Cancer Bulletin. Vol. 18 3. ed. 1974. pp. 93-99
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