Secondary Conditions among Males with Duchenne or Becker Muscular Dystrophy

Rebecca Latimer, Natalie Street, Kristin Caspers Conway, Kathy James, Christopher M Cunniff, Joyce Oleszek, Deborah Fox, Emma Ciafaloni, Christina Westfield, Pangaja Paramsothy

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Duchenne and Becker muscular dystrophy are X-linked neuromuscular disorders characterized by progressive muscle degeneration. Despite the involvement of multiple systems, secondary conditions among affected males have not been comprehensively described. Two hundred nine caregivers of affected males (aged 3-31 years) identified by the Muscular Dystrophy Surveillance, Tracking, and Research Network completed a mailed survey that included questions about secondary conditions impacting multiple body functions. The 5 most commonly reported conditions in males with Duchenne were cognitive deficits (38.4%), constipation (31.7%), anxiety (29.3%), depression (27.4%), and obesity (19.5%). Higher frequencies of anxiety, depression, and kidney stones were found among nonambulatory males compared to ambulatory males. Attention-deficit hyperactivity disorder (ADHD) was more common in ambulatory than nonambulatory males. These data support clinical care recommendations for monitoring of patients with Duchenne or Becker muscular dystrophy by a multidisciplinary team to prevent and treat conditions that may be secondary to the diagnosis.

Original languageEnglish (US)
Pages (from-to)663-670
Number of pages8
JournalJournal of Child Neurology
Volume32
Issue number7
DOIs
StatePublished - Jun 1 2017
Externally publishedYes

Fingerprint

Duchenne Muscular Dystrophy
Anxiety
Depression
Kidney Calculi
Muscular Dystrophies
Physiologic Monitoring
Constipation
Attention Deficit Disorder with Hyperactivity
Caregivers
Obesity
Muscles
Research

Keywords

  • Becker
  • comorbidities
  • Duchenne
  • muscular dystrophy
  • secondary conditions

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

Cite this

Latimer, R., Street, N., Conway, K. C., James, K., Cunniff, C. M., Oleszek, J., ... Paramsothy, P. (2017). Secondary Conditions among Males with Duchenne or Becker Muscular Dystrophy. Journal of Child Neurology, 32(7), 663-670. https://doi.org/10.1177/0883073817701368

Secondary Conditions among Males with Duchenne or Becker Muscular Dystrophy. / Latimer, Rebecca; Street, Natalie; Conway, Kristin Caspers; James, Kathy; Cunniff, Christopher M; Oleszek, Joyce; Fox, Deborah; Ciafaloni, Emma; Westfield, Christina; Paramsothy, Pangaja.

In: Journal of Child Neurology, Vol. 32, No. 7, 01.06.2017, p. 663-670.

Research output: Contribution to journalArticle

Latimer, R, Street, N, Conway, KC, James, K, Cunniff, CM, Oleszek, J, Fox, D, Ciafaloni, E, Westfield, C & Paramsothy, P 2017, 'Secondary Conditions among Males with Duchenne or Becker Muscular Dystrophy', Journal of Child Neurology, vol. 32, no. 7, pp. 663-670. https://doi.org/10.1177/0883073817701368
Latimer, Rebecca ; Street, Natalie ; Conway, Kristin Caspers ; James, Kathy ; Cunniff, Christopher M ; Oleszek, Joyce ; Fox, Deborah ; Ciafaloni, Emma ; Westfield, Christina ; Paramsothy, Pangaja. / Secondary Conditions among Males with Duchenne or Becker Muscular Dystrophy. In: Journal of Child Neurology. 2017 ; Vol. 32, No. 7. pp. 663-670.
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