Secretion systems and secreted proteins in gram-negative entomopathogenic bacteria: Their roles in insect virulence and beyond

Rebecca McQuade, S Patricia Stock

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

Many Gram-negative bacteria have evolved insect pathogenic lifestyles. In all cases, the ability to cause disease in insects involves specific bacterial proteins exported either to the surface, the extracellular environment, or the cytoplasm of the host cell. They also have several distinct mechanisms for secreting such proteins. In this review, we summarize the major protein secretion systems and discuss examples of secreted proteins that contribute to the virulence of a variety of Gram-negative entomopathogenic bacteria, including Photorhabdus, Xenorhabdus, Serratia, Yersinia, and Pseudomonas species. We also briefly summarize two classes of exported protein complexes, the PVC-like elements, and the Tc toxin complexes that were first described in entomopathogenic bacteria.

Original languageEnglish (US)
Article number68
JournalInsects
Volume9
Issue number2
DOIs
StatePublished - Jun 19 2018

Fingerprint

entomopathogenic bacteria
Gram-negative bacteria
virulence
secretion
insects
Photorhabdus
Xenorhabdus
insect diseases
Serratia
Yersinia
bacterial proteins
protein secretion
proteins
Pseudomonas
lifestyle
toxins
cytoplasm
cells

Keywords

  • Entomopathogens
  • Gram-negative bacteria
  • Host interactions
  • Secretion systems

ASJC Scopus subject areas

  • Insect Science

Cite this

Secretion systems and secreted proteins in gram-negative entomopathogenic bacteria : Their roles in insect virulence and beyond. / McQuade, Rebecca; Stock, S Patricia.

In: Insects, Vol. 9, No. 2, 68, 19.06.2018.

Research output: Contribution to journalReview article

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