Sedentary behavior and physical function

Objective evidence from the osteoarthritis initiative

Jungwha Lee, Rowland W. Chang, Linda Ehrlich-Jones, Chian K Kwoh, Michael Nevitt, Pamela A. Semanik, Leena Sharma, Min Woong Sohn, Jing Song, Dorothy D. Dunlop

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

Objective. Investigate the relationship between sedentary behavior and physical function in adults with knee osteoarthritis (OA), controlling for moderate-vigorous physical activity (MVPA) levels. Methods. Sedentary behavior was objectively measured by accelerometer on 1,168 participants ages 49-83 years in the Osteoarthritis Initiative with radiographic knee OA at the 48-month clinic visit. Physical function was assessed using 20-meter walk and chair stand testing. Sedentary behavior was identified by accelerometer activity counts/minute <100. The cross-sectional association between sedentary quartiles and physical function was examined by multiple linear regression, adjusting for demographic factors (age, sex, race/ethnicity, education level), health factors (comorbidity, body mass index, knee pain, knee OA severity, presence of knee symptoms), and average daily MVPA minutes. Results. Adults with knee OA spent two-thirds of their daily time in sedentary behavior. The average gait speed among the most sedentary quartile was 3.88 feet/second, which was significantly slower than the speed of the less sedentary groups (4.23, 4.33, and 4.33 feet/second, respectively). The average chair stand rate among the most sedentary group was significantly lower (25.9 stands/minute) than the rates of the less sedentary behavior groups (28.9, 29.1, and 31.1 stands/minute, respectively). These trends remained significant in multivariable analyses adjusted for demographic factors, health factors, and average daily MVPA minutes. Conclusion. Being less sedentary was related to better physical function in adults with knee OA independent of MVPA time. These findings support guidelines to encourage adults with knee OA to decrease time spent in sedentary behavior in order to improve physical function.

Original languageEnglish (US)
Pages (from-to)366-373
Number of pages8
JournalArthritis Care and Research
Volume67
Issue number3
DOIs
StatePublished - Mar 1 2015

Fingerprint

Knee Osteoarthritis
Osteoarthritis
Exercise
Knee
Demography
Ambulatory Care
Health Status
Comorbidity
Linear Models
Body Mass Index
Guidelines
Education
Pain
Health

ASJC Scopus subject areas

  • Rheumatology

Cite this

Lee, J., Chang, R. W., Ehrlich-Jones, L., Kwoh, C. K., Nevitt, M., Semanik, P. A., ... Dunlop, D. D. (2015). Sedentary behavior and physical function: Objective evidence from the osteoarthritis initiative. Arthritis Care and Research, 67(3), 366-373. https://doi.org/10.1002/acr.22432

Sedentary behavior and physical function : Objective evidence from the osteoarthritis initiative. / Lee, Jungwha; Chang, Rowland W.; Ehrlich-Jones, Linda; Kwoh, Chian K; Nevitt, Michael; Semanik, Pamela A.; Sharma, Leena; Sohn, Min Woong; Song, Jing; Dunlop, Dorothy D.

In: Arthritis Care and Research, Vol. 67, No. 3, 01.03.2015, p. 366-373.

Research output: Contribution to journalArticle

Lee, J, Chang, RW, Ehrlich-Jones, L, Kwoh, CK, Nevitt, M, Semanik, PA, Sharma, L, Sohn, MW, Song, J & Dunlop, DD 2015, 'Sedentary behavior and physical function: Objective evidence from the osteoarthritis initiative', Arthritis Care and Research, vol. 67, no. 3, pp. 366-373. https://doi.org/10.1002/acr.22432
Lee, Jungwha ; Chang, Rowland W. ; Ehrlich-Jones, Linda ; Kwoh, Chian K ; Nevitt, Michael ; Semanik, Pamela A. ; Sharma, Leena ; Sohn, Min Woong ; Song, Jing ; Dunlop, Dorothy D. / Sedentary behavior and physical function : Objective evidence from the osteoarthritis initiative. In: Arthritis Care and Research. 2015 ; Vol. 67, No. 3. pp. 366-373.
@article{2a1448f9bf524f219d228d9c395d5641,
title = "Sedentary behavior and physical function: Objective evidence from the osteoarthritis initiative",
abstract = "Objective. Investigate the relationship between sedentary behavior and physical function in adults with knee osteoarthritis (OA), controlling for moderate-vigorous physical activity (MVPA) levels. Methods. Sedentary behavior was objectively measured by accelerometer on 1,168 participants ages 49-83 years in the Osteoarthritis Initiative with radiographic knee OA at the 48-month clinic visit. Physical function was assessed using 20-meter walk and chair stand testing. Sedentary behavior was identified by accelerometer activity counts/minute <100. The cross-sectional association between sedentary quartiles and physical function was examined by multiple linear regression, adjusting for demographic factors (age, sex, race/ethnicity, education level), health factors (comorbidity, body mass index, knee pain, knee OA severity, presence of knee symptoms), and average daily MVPA minutes. Results. Adults with knee OA spent two-thirds of their daily time in sedentary behavior. The average gait speed among the most sedentary quartile was 3.88 feet/second, which was significantly slower than the speed of the less sedentary groups (4.23, 4.33, and 4.33 feet/second, respectively). The average chair stand rate among the most sedentary group was significantly lower (25.9 stands/minute) than the rates of the less sedentary behavior groups (28.9, 29.1, and 31.1 stands/minute, respectively). These trends remained significant in multivariable analyses adjusted for demographic factors, health factors, and average daily MVPA minutes. Conclusion. Being less sedentary was related to better physical function in adults with knee OA independent of MVPA time. These findings support guidelines to encourage adults with knee OA to decrease time spent in sedentary behavior in order to improve physical function.",
author = "Jungwha Lee and Chang, {Rowland W.} and Linda Ehrlich-Jones and Kwoh, {Chian K} and Michael Nevitt and Semanik, {Pamela A.} and Leena Sharma and Sohn, {Min Woong} and Jing Song and Dunlop, {Dorothy D.}",
year = "2015",
month = "3",
day = "1",
doi = "10.1002/acr.22432",
language = "English (US)",
volume = "67",
pages = "366--373",
journal = "Arthritis and Rheumatology",
issn = "2326-5191",
publisher = "John Wiley and Sons Ltd",
number = "3",

}

TY - JOUR

T1 - Sedentary behavior and physical function

T2 - Objective evidence from the osteoarthritis initiative

AU - Lee, Jungwha

AU - Chang, Rowland W.

AU - Ehrlich-Jones, Linda

AU - Kwoh, Chian K

AU - Nevitt, Michael

AU - Semanik, Pamela A.

AU - Sharma, Leena

AU - Sohn, Min Woong

AU - Song, Jing

AU - Dunlop, Dorothy D.

PY - 2015/3/1

Y1 - 2015/3/1

N2 - Objective. Investigate the relationship between sedentary behavior and physical function in adults with knee osteoarthritis (OA), controlling for moderate-vigorous physical activity (MVPA) levels. Methods. Sedentary behavior was objectively measured by accelerometer on 1,168 participants ages 49-83 years in the Osteoarthritis Initiative with radiographic knee OA at the 48-month clinic visit. Physical function was assessed using 20-meter walk and chair stand testing. Sedentary behavior was identified by accelerometer activity counts/minute <100. The cross-sectional association between sedentary quartiles and physical function was examined by multiple linear regression, adjusting for demographic factors (age, sex, race/ethnicity, education level), health factors (comorbidity, body mass index, knee pain, knee OA severity, presence of knee symptoms), and average daily MVPA minutes. Results. Adults with knee OA spent two-thirds of their daily time in sedentary behavior. The average gait speed among the most sedentary quartile was 3.88 feet/second, which was significantly slower than the speed of the less sedentary groups (4.23, 4.33, and 4.33 feet/second, respectively). The average chair stand rate among the most sedentary group was significantly lower (25.9 stands/minute) than the rates of the less sedentary behavior groups (28.9, 29.1, and 31.1 stands/minute, respectively). These trends remained significant in multivariable analyses adjusted for demographic factors, health factors, and average daily MVPA minutes. Conclusion. Being less sedentary was related to better physical function in adults with knee OA independent of MVPA time. These findings support guidelines to encourage adults with knee OA to decrease time spent in sedentary behavior in order to improve physical function.

AB - Objective. Investigate the relationship between sedentary behavior and physical function in adults with knee osteoarthritis (OA), controlling for moderate-vigorous physical activity (MVPA) levels. Methods. Sedentary behavior was objectively measured by accelerometer on 1,168 participants ages 49-83 years in the Osteoarthritis Initiative with radiographic knee OA at the 48-month clinic visit. Physical function was assessed using 20-meter walk and chair stand testing. Sedentary behavior was identified by accelerometer activity counts/minute <100. The cross-sectional association between sedentary quartiles and physical function was examined by multiple linear regression, adjusting for demographic factors (age, sex, race/ethnicity, education level), health factors (comorbidity, body mass index, knee pain, knee OA severity, presence of knee symptoms), and average daily MVPA minutes. Results. Adults with knee OA spent two-thirds of their daily time in sedentary behavior. The average gait speed among the most sedentary quartile was 3.88 feet/second, which was significantly slower than the speed of the less sedentary groups (4.23, 4.33, and 4.33 feet/second, respectively). The average chair stand rate among the most sedentary group was significantly lower (25.9 stands/minute) than the rates of the less sedentary behavior groups (28.9, 29.1, and 31.1 stands/minute, respectively). These trends remained significant in multivariable analyses adjusted for demographic factors, health factors, and average daily MVPA minutes. Conclusion. Being less sedentary was related to better physical function in adults with knee OA independent of MVPA time. These findings support guidelines to encourage adults with knee OA to decrease time spent in sedentary behavior in order to improve physical function.

UR - http://www.scopus.com/inward/record.url?scp=84923287723&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84923287723&partnerID=8YFLogxK

U2 - 10.1002/acr.22432

DO - 10.1002/acr.22432

M3 - Article

VL - 67

SP - 366

EP - 373

JO - Arthritis and Rheumatology

JF - Arthritis and Rheumatology

SN - 2326-5191

IS - 3

ER -