Sensing bacteria, without bitterness?

Research output: Contribution to journalComment/debate

8 Scopus citations

Abstract

In addition to their recognized roles in intra- and inter-species signaling, bacterial quorum-sensing molecules have been implicated in inter-kingdom signaling. A new study in Pseudomonas aeruginosa suggests that mammalian bitter taste receptors may recognize bacterial quorum sensing molecules, and widens the scope of such inter-kingdom communication. Intestinal cells also harbor these receptors, but whether they eavesdrop on bacterial conversations remains an open question.

Original languageEnglish (US)
Pages (from-to)91-93
Number of pages3
JournalGut microbes
Volume4
Issue number2
DOIs
StatePublished - Mar 1 2013

Keywords

  • Acyl homoserine lactone
  • Bitter
  • Quorum sensing
  • T2R38
  • Taste receptor

ASJC Scopus subject areas

  • Microbiology
  • Gastroenterology
  • Microbiology (medical)
  • Infectious Diseases

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